Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376320 | 0.87 | DPP4 (0.65) | DPP4 | |
| SCHEMBL13570514 | 0.87 | F2 (0.53) | DPP4 | |
| SCHEMBL2170169 | 0.87 | SCN9A (0.54) | AGTR2DPP4 | |
| SCHEMBL8536863 | 0.85 | DPP4 (0.49) | DPP4 | |
| SCHEMBL22333690 | 0.84 | AGTR2 (0.60) | AGTR2 | |
| SCHEMBL22333647 | 0.84 | AGTR2 (0.60) | AGTR2 | |
| SCHEMBL28797928 | 0.83 | ERAP2 (0.48) | DPP4 | |
| SCHEMBL3733552 | 0.83 | LMNA (0.52) | DPP4 | |
| SCHEMBL17220302 | 0.82 | GAA (0.54) | DPP4 | |
| SCHEMBL2176481 | 0.82 | KCNH2 (0.47) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268418-A1 | PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS | Applied Research Systems ARS Holding N.V. (AN) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074769-A1 | PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-10-11 | — | — | WO | disclosed |