SCHEMBL1357375

SCHEMBL1357375

CCCCCCOC(=O)c1ccc(C(=O)OCCCCCC)o1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
TSHR P16473 3/20 0.62
LMNA P02545 2/20 0.62
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAPK1 P28482 1/20 0.59
NPC1 O15118 1/20 0.57
MAPT P10636 1/20 0.57
RAB9A P51151 1/20 0.57
TDP1 Q9NUW8 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
KDM4E B2RXH2 1/20 0.54
POLB P06746 1/20 0.54
HSD17B10 Q99714 1/20 0.54
ESR1 P03372 3/20 0.53
AKR1C4 P17516 1/20 0.53
AKR1C3 P42330 1/20 0.53
AKR1C2 P52895 1/20 0.53
AKR1C1 Q04828 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16268280 1.00 ALDH1A1 (0.62) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL28048651 1.00 ALDH1A1 (0.62) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL16268099 1.00 ALDH1A1 (0.62) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL15422580 1.00 ALDH1A1 (0.62) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL16267961 1.00 ALDH1A1 (0.62) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL28708367 1.00 ALDH1A1 (0.62) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL18154629 0.98 TSHR (0.61) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL28825285 0.94 MEN1 (0.66) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL28700897 0.94 ALDH1A1 (0.55) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL28684817 0.94 ALDH1A1 (0.55) ALDH1A1TSHRLMNATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029579-B2 Method of synthesizing low color furan diesters EASTMAN CHEMICAL COMPANY (US) 2015-05-12 US claimed
US-9006470-B2 Method of synthesizing low color furan diesters EASTMAN CHEMICAL COMPANY (US) 2015-04-14 US claimed
WO-2014074484-A1 METHOD OF SYNTHESIZING LOW COLOR FURAN DIESTERS EASTMAN CHEMICAL COMPANY (US) 2014-05-15 WO claimed
WO-2014074482-A1 METHOD OF SYNTHESIZING LOW COLOR FURAN DIESTERS EASTMAN CHEMICAL COMPANY (US) 2014-05-15 WO claimed
US-20140128623-A1 Method of Synthesizing Low Color Furan Diesters EASTMAN CHEMICAL COMPANY (US) 2014-05-08 US claimed
US-20140128624-A1 METHOD OF SYNTHESIZING LOW COLOR FURAN DIESTERS EASTMAN CHEMICAL COMPANY (US) 2014-05-08 US claimed
CN-115028973-B Bio-based auxiliary agent for promoting rapid crystallization of polylactic acid and application thereof 中国科学院宁波材料技术与工程研究所 2024-12-03 CN disclosed
CN-114163407-B Furan ring component for inhibiting or killing microorganism, product containing the same and application thereof 中国科学院宁波材料技术与工程研究所 2023-10-24 CN disclosed
EP-3548474-B1 ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) ARCHER DANIELS MIDLAND CO (US) 2023-07-05 EP disclosed
CN-115197403-B Crystalline degradable polyester based on 1, 3-butanediol and preparation method thereof 东北师范大学 2023-05-26 CN disclosed
CN-115028973-A Bio-based additive for promoting rapid crystallization of polylactic acid and application thereof 中国科学院宁波材料技术与工程研究所 2022-09-09 CN disclosed
CN-114163407-A Furan ring composition for inhibiting or killing microorganism, product containing furan ring composition and application of furan ring composition 中国科学院宁波材料技术与工程研究所 2022-03-11 CN disclosed
CN-111440062-A Method for preparing adipic acid from furan-2, 5-dicarboxylic acid ester derivatives 中国石油化工股份有限公司 2020-07-24 CN disclosed
WO-2014074484-A1 METHOD OF SYNTHESIZING LOW COLOR FURAN DIESTERS EASTMAN CHEMICAL COMPANY (US) 2014-05-15 WO disclosed
US-20140128623-A1 Method of Synthesizing Low Color Furan Diesters EASTMAN CHEMICAL COMPANY (US) 2014-05-08 US disclosed
US-20140128624-A1 METHOD OF SYNTHESIZING LOW COLOR FURAN DIESTERS EASTMAN CHEMICAL COMPANY (US) 2014-05-08 US disclosed
CN-103570925-A Biodegradable polyester and preparation method thereof SHANGHAI GENIUS ADVANCED MAT 2014-02-12 CN disclosed
US-20110282020-A1 PROCESS FOR PREPARING A POLYMER HAVING A 2,5-FURANDICARBOXYLATE MOIETY WITHIN THE POLYMER BACKBONE AND SUCH (CO)POLYMERS FURANIX TECHNOLOGIES B.V. (NL) 2011-11-17 US disclosed
EP-2370496-A1 A PROCESS FOR PREPARING A POLYMER HAVING A 2,5-FURANDICARBOXYLATE MOIETY WITHIN THE POLYMER BACKBONE AND SUCH (CO)POLYMERS Furanix Technologies B.V. (NL) 2011-10-05 EP disclosed
WO-2010077133-A1 A PROCESS FOR PREPARING A POLYMER HAVING A 2,5-FURANDICARBOXYLATE MOIETY WITHIN THE POLYMER BACKBONE AND SUCH (CO)POLYMERS FURANIX TECHNOLOGIES B.V. (NL) 2010-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140128623-A1 Method of Synthesizing Low Color Furan Diesters PCCA, FLAD1, PFAS ALDH1A1 43/4885TSHR 3856/4885LMNA 1726/4885
US-20140128624-A1 METHOD OF SYNTHESIZING LOW COLOR FURAN DIESTERS CYP4F2, HPD, HSD17B14 ALDH1A1 265/4885TSHR 4732/4885LMNA 3557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.