SCHEMBL135744

SCHEMBL135744

ON(O)CCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.58
AOC3 Q16853 2/20 0.54
TDP1 Q9NUW8 2/20 0.52
ALOX5 P09917 3/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
OPRK1 P41145 1/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4968152 0.84 CYP1A2 (0.62) TAAR1AOC3TDP1ALOX5CYP1A2
SCHEMBL28929226 0.81 SIGMAR1 (0.64) ALOX5SIGMAR1
SCHEMBL28457555 0.81 SIGMAR1 (0.64) ALOX5SIGMAR1
SCHEMBL28422310 0.80 TAAR1 (0.67) TAAR1AOC3TDP1ALOX5CYP1A2
SCHEMBL9353620 0.78 TAAR1 (0.52) TAAR1AOC3TDP1ALOX5CYP1A2
SCHEMBL8606673 0.78 CYP1A2 (0.79) TAAR1AOC3TDP1ALOX5CYP1A2
SCHEMBL1344100 0.78 OPRK1 (0.65) TAAR1AOC3TDP1OPRK1ALDH1A1
SCHEMBL7075328 0.77 AOC3 (0.59) TAAR1AOC3TDP1ALOX5CYP1A2
SCHEMBL1520687 0.77 ALOX5 (0.65) TAAR1AOC3TDP1ALOX5CYP1A2
Hydrogen Peroxide SCHEMBL10839871 0.76 TDP1 (0.71) TAAR1TDP1ALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118923830-A Honey dew added with food ingredients and production process thereof 武汉安孕堂创新科技有限公司 2024-11-12 CN claimed
EP-4206236-A1 COMPOUNDS, THEIR SYNTHESIS AND COMPOSITIONS COMPRISING THE COMPOUNDS FOR ENHANCED DEPOSITION OF POLYMERS ONTO HAIR SURFACES Kao Corporation (JP) 2023-07-05 EP claimed
CN-116084019-A Substituent regulation-based hybrid organic-inorganic perovskite crystal and synthesis method thereof 南开大学 2023-05-09 CN claimed
CN-111146430-B Porous core-shell structure silicon-carbon negative electrode material for lithium ion battery and preparation method thereof 马鞍山科达普锐能源科技有限公司 2022-08-23 CN claimed
CN-111470822-A Preparation method of concrete 海娇 2020-07-31 CN claimed
WO-2019190402-A1 BIOCOMPATIBLE OPHTHALMIC DEVICE SINGAPORE HEALTH SERVICES PTE LTD (SG) 2019-10-03 WO claimed
EP-2064251-B1 BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR KENSEY NASH CORP (US) 2017-10-25 EP claimed
US-9115289-B2 Multibranched bioadhesive compounds and synthetic methods therefor KENSEY NASH CORPORATION (US) 2015-08-25 US claimed
US-8907045-B2 Biocompatible adhesive polymers EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-09 US claimed
US-20140041802-A1 BIOCOMPATIBLE ADHESIVE POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-02-13 US claimed
EP-2348835-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS KNC NER Acquisition Sub, Inc. (US) 2011-08-03 EP claimed
WO-2010091298-A1 MULTIBRANCHED BIOADHESIVE COMPOUNDS AND SYNTHETIC METHODS THEREFOR NERITES CORPORATION (US) 2010-08-12 WO claimed
US-20100113828-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS NERITES CORPORATION (US) 2010-05-06 US claimed
WO-2010037045-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS NERITES CORPORATION (US) 2010-04-01 WO claimed
WO-2008154083-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES PROTEO TECH INC. (US) 2008-12-18 WO claimed
US-5310539-A Paramagnetic rare earth metals, magnetic resonance imaging BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-05-10 US claimed
EP-0580734-A1 MELANIN-BASED AGENTS FOR IMAGE ENHANCEMENT BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-02-02 EP claimed
EP-0395529-B1 Hydroxyphenethylamine derivative and its salts, method of preparation, medical application and use as specific pharmacological tool ROUSSEL UCLAF (FR) 1993-11-03 EP claimed
WO-1992018166-A1 MELANIN-BASED AGENTS FOR IMAGE ENHANCEMENT BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-10-29 WO claimed
EP-0395529-A1 Hydroxyphenethylamine derivative and its salts, method of preparation, medical application and use as specific pharmacological tool ROUSSEL-UCLAF (FR) 1990-10-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113828-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS COMT, HAAO, PNMT TAAR1 2022/4885AOC3 127/4885TDP1 3032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.