SCHEMBL15023217

SCHEMBL15023217

CC(C)CC(O)OCC(O)CO

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.35
LMNA P02545 3/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 2/20 0.32
KDM4E B2RXH2 2/20 0.32
AGTR1 P30556 1/20 0.32
DUSP3 P51452 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK1 P28482 1/20 0.31
DGKA P23743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1619852 0.83 LMNA (0.40) USP2LMNAALDH1A1CYP1A2KDM4E
SCHEMBL4623780 0.82 USP2 (0.35) USP2LMNATSHRALDH1A1TDP1
SCHEMBL9668195 0.80 ALDH1A1 (0.31) TSHRALDH1A1MAPK1
SCHEMBL17237504 0.80 USP2 (0.34) USP2LMNATSHRALDH1A1TDP1
SCHEMBL1357902 0.78 LMNA (0.44) USP2LMNATSHRALDH1A1CYP1A2
SCHEMBL888322 0.76 TSHR (0.43) USP2LMNATSHRALDH1A1TDP1
SCHEMBL1487123 0.75
SCHEMBL5027030 0.75
SCHEMBL7624990 0.75
SCHEMBL764019 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2320863-B1 CLEANSING COMPOSITION KAO GERMANY GMBH (DE) 2018-05-16 EP claimed
EP-2320855-B1 CONDITIONING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2017-12-27 EP claimed
EP-2320862-B1 CLEANSING COMPOSITION KAO GERMANY GMBH (DE) 2016-04-27 EP claimed
EP-2320856-B1 CONDITIONING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2015-11-11 EP claimed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 US disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 EP disclosed
US-20200283650-A1 INK COMPOSITION SEIKO EPSON CORPORATION (JP) 2020-09-10 US disclosed
WO-2017075257-A2 HIGH INTENSITY SWEETENERS SENOMYX, INC. (US) 2017-05-04 WO disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 US disclosed
US-9029293-B2 Tobacco axillary bud inhibitor and tobacco axillary bud-inhibiting method SDS BIOTECH K.K. (JP) 2015-05-12 US disclosed
US-8865624-B2 Inhibitor for tobacco axillary bud growth and method for inhibiting tobacco axillary bud growth SDS BIOTECH K.K. (JP) 2014-10-21 US disclosed
US-20140121112-A1 TOBACCO AXILLARY BUD INHIBITOR AND TOBACCO AXILLARY BUD-INHIBITING METHOD SDS BIOTECH K.K. (JP) 2014-05-01 US disclosed
US-20130157857-A1 INHIBITOR FOR TOBACCO AXILLARY BUD GROWTH AND METHOD FOR INHIBITING TOBACCO AXILLARY BUD GROWTH SDS BIOTECH K.K. (JP) 2013-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 USP2 4693/4885LMNA 4834/4885TSHR 3246/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 USP2 3953/4885LMNA 4440/4885TSHR 2120/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 USP2 4693/4885LMNA 4834/4885TSHR 3246/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D USP2 3149/4885LMNA 4541/4885TSHR 2063/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 USP2 4693/4885LMNA 4834/4885TSHR 3246/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 USP2 4693/4885LMNA 4834/4885TSHR 3246/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 USP2 4285/4885LMNA 4164/4885TSHR 2031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.