Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21127229 | 0.91 | ADRA2B (0.50) | PYCR1SLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL14174895 | 0.82 | MEN1 (0.47) | PYCR1SLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL23059839 | 0.80 | PYCR1 (0.55) | PYCR1SLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL2582095 | 0.80 | ADRA2B (0.42) | PYCR1SLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL25640176 | 0.80 | PYCR1 (0.46) | PYCR1SLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL24973992 | 0.80 | HTR2A (0.52) | PYCR1SLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL13532083 | 0.80 | PYCR1 (0.48) | PYCR1SLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL19033246 | 0.80 | ALDH1A1 (0.54) | PYCR1SLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL5204980 | 0.80 | MAPT (0.46) | PYCR1SLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL819942 | 0.79 | HDAC1 (0.52) | PYCR1SLC6A2SLC6A4CNR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140283199-A1 | Signaling Compositions, Methods, and Systems for Effecting Plant Burndown and Herbicide Enhancement | KamTec (US) | 2014-09-18 | — | — | US | claimed |
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-06-13 | — | — | US | disclosed |
| US-20190092758-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-03-28 | — | — | US | disclosed |
| EP-1950199-B1 | Proline derivatives and use thereof as drugs | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-12-02 | — | — | EP | disclosed |
| EP-1857459-A2 | Pyrazolopyrimidine compound and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2007-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | FUT6, DDOST, MGAM | PYCR1 3487/4885SLC6A2 4089/4885SLC6A4 2681/4885 |
| US-20190092758-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | TLR9, TLR1, TLR3 | PYCR1 3481/4885SLC6A2 3671/4885SLC6A4 2287/4885 |
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | FUT6, DDOST, MGAM | PYCR1 3487/4885SLC6A2 4089/4885SLC6A4 2681/4885 |
| US-20140283199-A1 | Signaling Compositions, Methods, and Systems for Effecting Plant Burndown and Herbicide Enhancement | BOLA2; BOLA2B, DBNL, EBPL | PYCR1 3633/4885SLC6A2 3277/4885SLC6A4 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.