Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | NAAA | Q02083 | 2/20 | 0.54 |
| ▸ | ESRRG | P62508 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4389040 | 0.98 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2PLK1TMEM97SIGMAR1 | |
| SCHEMBL10949132 | 0.89 | PLK1 (0.70) | L3MBTL1SMN1; SMN2PLK1TMEM97SIGMAR1 | |
| SCHEMBL10950073 | 0.89 | PLK1 (0.64) | L3MBTL1SMN1; SMN2PLK1TMEM97SIGMAR1 | |
| SCHEMBL8122188 | 0.87 | SMN1; SMN2 (0.63) | L3MBTL1SMN1; SMN2TMEM97SIGMAR1NAAA | |
| SCHEMBL26553937 | 0.87 | L3MBTL1 (0.60) | L3MBTL1PLK1TMEM97SIGMAR1NAAA | |
| Hydrochloric Acid SCHEMBL25401659 | 0.85 | L3MBTL1 (0.58) | L3MBTL1PLK1TMEM97SIGMAR1NAAA | |
| SCHEMBL26553938 | 0.85 | THRA (0.57) | L3MBTL1PLK1NAAACA2MEN1 | |
| SCHEMBL28326194 | 0.85 | L3MBTL1 (0.73) | L3MBTL1SMN1; SMN2NAAACA2NPC1 | |
| SCHEMBL13375744 | 0.84 | L3MBTL1 (0.69) | L3MBTL1SMN1; SMN2PLK1TMEM97SIGMAR1 | |
| SCHEMBL23840600 | 0.84 | HPGD (0.62) | L3MBTL1SMN1; SMN2TMEM97SIGMAR1ESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |