Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653289 | 0.95 | HTT (0.51) | HDAC1HDAC3HDAC2HDAC6HDAC10 | |
| SCHEMBL13593283 | 0.82 | CDC25A (0.47) | HDAC1HDAC3HDAC2HDAC6HDAC10 | |
| SCHEMBL21665202 | 0.80 | HTT (0.60) | HDAC1HDAC3HDAC2HDAC6HDAC10 | |
| SCHEMBL38666280 | 0.80 | RAB9A (0.63) | HDAC2HDAC6HDAC8MEN1KMT2A | |
| SCHEMBL31154603 | 0.80 | MAPK1 (0.63) | MEN1KMT2ASOAT1HTTCETP | |
| SCHEMBL13462509 | 0.80 | MAPK1 (0.63) | MEN1KMT2ASOAT1HTTCETP | |
| SCHEMBL7719067 | 0.80 | HDAC3 (0.61) | HDAC1HDAC3HDAC2HDAC6HDAC10 | |
| SCHEMBL7717055 | 0.80 | HDAC3 (0.61) | HDAC1HDAC3HDAC2HDAC6HDAC10 | |
| SCHEMBL7717024 | 0.80 | HDAC3 (0.61) | HDAC1HDAC3HDAC2HDAC6HDAC10 | |
| SCHEMBL16010983 | 0.78 | LMNA (0.60) | HDAC1HDAC3HDAC2HDAC6HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324540-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| US-7553872-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324540-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | ABCB4, ABCB7, ALPP | HDAC1 888/4885HDAC3 1377/4885HDAC2 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.