Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 8/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13596361 | 0.84 | MEN1 (0.50) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL13888696 | 0.84 | MEN1 (0.50) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL13888704 | 0.82 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL17323633 | 0.82 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL20697893 | 0.82 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL20697894 | 0.82 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL17323640 | 0.82 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MMEACECPA1 | |
| SCHEMBL21896518 | 0.81 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL20707087 | 0.81 | CTSS (0.47) | ALDH1A1L3MBTL1CTSSCTSKMME | |
| SCHEMBL2735760 | 0.80 | ENPEP (0.52) | ALDH1A1L3MBTL1CTSSCTSKMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638526-B2 | Azetidine derivatives useful in treating pain, diabetes and disorders of lipid metabolism | SCHERING CORPORATION (US) | 2009-12-29 | — | — | US | disclosed |
| US-20080089858-A1 | AZETIDINE DERIVATIVES USEFUL IN TREATING PAIN, DIABETES AND DISORDERS OF LIPID METABOLISM | SCHERING CORPORATION | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080089858-A1 | AZETIDINE DERIVATIVES USEFUL IN TREATING PAIN, DIABETES AND DISORDERS OF LIPID METABOLISM | GPR119, PNLIP, CYP46A1 | ALDH1A1 692/4885L3MBTL1 4079/4885CTSS 3426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.