SCHEMBL1359631

SCHEMBL1359631

FC(C(F)(F)F)C(F)(F)Oc1cc(Br)[c]c2cccnc12

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.33
DYRK1A Q13627 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4161311 0.70 KIF11 (0.33)
SCHEMBL10683029 0.69 LTA4H (0.41) RECQLALDH1A1TSHRHSD17B10
SCHEMBL10683094 0.69 ALDH1A1 (0.43) RECQLALDH1A1TSHRHSD17B10
SCHEMBL1360496 0.66 ALDH1A1 (0.45) RECQLALDH1A1TSHRHSD17B10
SCHEMBL7751671 0.65 ALDH1A1 (0.46) RECQLALDH1A1TSHRHSD17B10
SCHEMBL1360413 0.61 ALDH1A1 (0.41) RECQLALDH1A1TSHRHSD17B10
SCHEMBL7911138 0.61 RECQL (0.42) RECQLALDH1A1TSHRHSD17B10
SCHEMBL4580107 0.60 ALDH1A1 (0.40) RECQLALDH1A1TSHRHSD17B10
SCHEMBL1360550 0.60 ALDH1A1 (0.40) RECQLALDH1A1TSHRHSD17B10
SCHEMBL7751907 0.60 ALDH1A1 (0.41) RECQLALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067638-B2 Amide derivative and insecticide containing the same MITSUI CHEMICALS, INC. (JP) 2011-11-29 US disclosed
EP-1911751-A1 AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND Mitsui Chemicals, Inc. (JP) 2008-04-16 EP disclosed