Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12084014 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TDP1TRPA1 | |
| SCHEMBL9357262 | 0.74 | TDP1 (0.41) | LMNATDP1 | |
| SCHEMBL22301098 | 0.74 | ALDH1A1 (0.30) | ALDH1A1TDP1 | |
| SCHEMBL13303095 | 0.72 | — | — | |
| SCHEMBL13303091 | 0.72 | TSHR (0.42) | ALDH1A1LMNA | |
| SCHEMBL12175269 | 0.69 | — | — | |
| SCHEMBL6883144 | 0.69 | CA12 (0.47) | ALDH1A1LMNATRPA1 | |
| SCHEMBL816479 | 0.69 | PAOX (0.41) | ALDH1A1LMNASLC15A2 | |
| SCHEMBL13464165 | 0.67 | — | — | |
| SCHEMBL416818 | 0.65 | TRPA1 (0.50) | ALDH1A1LMNASLC15A2TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090320718-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| US-20090320718-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| WO-2008003447-A2 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090320718-A1 | FLUOROSURFACTANTS | FPR3, Q6ZSR9, SGMS2 | ALDH1A1 4113/4885LMNA 1609/4885SLC15A2 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.