Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13600039 | 0.80 | KMT2A (0.34) | FPR2PROKR1HTR2AHTR2C | |
| SCHEMBL13600047 | 0.78 | SCD (0.37) | — | |
| SCHEMBL38657763 | 0.78 | HTR2A (0.35) | FPR2PROKR1HTR2AHTR2C | |
| SCHEMBL12893617 | 0.76 | HRH3 (0.42) | HRH3 | |
| SCHEMBL5970964 | 0.72 | GPR119 (0.56) | — | |
| SCHEMBL13003252 | 0.72 | ACLY (0.37) | FPR2PROKR1HRH3 | |
| SCHEMBL13600166 | 0.69 | LIPE (0.42) | FPR2PROKR1HRH3ACACB | |
| SCHEMBL13600014 | 0.69 | MAPK14 (0.40) | ACACB | |
| SCHEMBL13600105 | 0.69 | CCR5 (0.43) | HRH3 | |
| SCHEMBL10254954 | 0.69 | FPR2 (0.39) | FPR2PROKR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638531-B2 | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists | SCHERING CORPORATION (US) | 2009-12-29 | — | — | US | disclosed |
| US-20070167435-A1 | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists | SCHERING CORPORATION | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167435-A1 | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists | HRH4, HRH3, HRH2 | FPR2 505/4885PROKR1 226/4885HTR2A 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.