Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12773981 | 0.86 | GNAI3 (0.36) | ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL12774077 | 0.86 | ACHE (0.37) | ALDH1A1SIGMAR1KDM4E | |
| SCHEMBL12881669 | 0.86 | ALDH1A1 (0.34) | ALDH1A1TSHRSIGMAR1LMNASMN1; SMN2 | |
| SCHEMBL12881653 | 0.86 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL12774035 | 0.86 | L3MBTL3 (0.36) | ALDH1A1SIGMAR1KDM4E | |
| SCHEMBL13601625 | 0.85 | TP53 (0.43) | ALDH1A1SIGMAR1SMN1; SMN2PAOX | |
| SCHEMBL12881701 | 0.84 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12881686 | 0.81 | MEN1 (0.35) | ALDH1A1SIGMAR1 | |
| SCHEMBL13601361 | 0.81 | MAPT (0.38) | ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL1127888 | 0.80 | ALDH1A1 (0.45) | ALDH1A1TSHRSIGMAR1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625886-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-01 | — | — | US | disclosed |