Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601657 | 0.89 | MYC (0.42) | TAS2R14SCN9AMYCDHODHRXRA | |
| SCHEMBL13601658 | 0.88 | TAS2R14 (0.42) | TAS2R14SCN9AMYCAKR1C3AKR1C2 | |
| SCHEMBL13601588 | 0.88 | AKR1C3 (0.50) | TAS2R14SCN9AMYCHSD11B1AKR1C3 | |
| SCHEMBL13601671 | 0.78 | RORC (0.47) | HSD11B1AKR1C3AKR1C2ALDH1A1MRGPRX4 | |
| SCHEMBL13601650 | 0.77 | DHODH (0.47) | MYCDHODHALDH1A1HPGD | |
| SCHEMBL13601647 | 0.77 | ACMSD (0.50) | MYCDHODHALDH1A1 | |
| SCHEMBL30532289 | 0.75 | TAS2R14 (0.46) | TAS2R14SCN9AAKR1C3AKR1C2RXRA | |
| SCHEMBL28570642 | 0.75 | TAS2R14 (0.46) | TAS2R14SCN9AAKR1C3AKR1C2RXRA | |
| SCHEMBL1195140 | 0.75 | TAS2R14 (0.51) | TAS2R14DHODHHDAC6ALDH1A1HPGD | |
| SCHEMBL544646 | 0.74 | ALDH1A1 (0.50) | TAS2R14MYCHSD11B1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | TAS2R14 4160/4885SCN9A 2824/4885MYC 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.