SCHEMBL544646

SCHEMBL544646

O=C(O)c1cccc(-c2ccccc2C(F)(F)F)c1C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
HPGD P15428 1/20 0.50
TAS2R14 Q9NYV8 2/20 0.49
FABP4 P15090 1/20 0.48
KMO O15229 2/20 0.46
LMNA P02545 2/20 0.45
GAA P10253 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PARP1 P09874 1/20 0.43
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
HNF4A P41235 1/20 0.42
ALOX15 P16050 1/20 0.42
KCNK3 O14649 1/20 0.41
KCNK9 Q9NPC2 1/20 0.41
MYC P01106 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 1/20 0.41
HSD11B1 P28845 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL940482 0.89 HSD17B10 (0.48) ALDH1A1HPGDTAS2R14FABP4LMNA
SCHEMBL344491 0.86 ALDH1A1 (0.56) ALDH1A1HPGDTAS2R14FABP4KMO
SCHEMBL28636304 0.85 ALDH1A1 (0.51) ALDH1A1HPGDTAS2R14FABP4KMO
SCHEMBL1195140 0.84 TAS2R14 (0.51) ALDH1A1HPGDTAS2R14FABP4LMNA
SCHEMBL28160264 0.83 ALDH1A1 (0.50) ALDH1A1HPGDTAS2R14FABP4KMO
SCHEMBL2174123 0.83 HNF4A (0.58) ALDH1A1TAS2R14FABP4LMNAMEN1
SCHEMBL23908710 0.83 ALDH1A1 (0.47) ALDH1A1HPGDTAS2R14FABP4KMO
SCHEMBL10907542 0.83 LMNA (0.41) ALDH1A1HPGDTAS2R14FABP4KMO
SCHEMBL28484672 0.82 TAS2R14 (0.50) ALDH1A1HPGDTAS2R14FABP4LMNA
SCHEMBL29188681 0.82 ALDH1A1 (0.49) ALDH1A1HPGDTAS2R14FABP4KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110330-B2 a mixture of binder resins, colorants, release agent and zeolites, used to form high quality images, by electrography RICOH COMPANY, LTD. (JP) 2012-02-07 US disclosed
US-20080131797-A1 Toner, developer, toner container, process cartridge, image forming method, and image forming apparatus RICOH COMPANY, LTD. (JP) 2008-06-05 US disclosed