Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16900169 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7011056 | 0.81 | NPC1 (0.67) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8790468 | 0.75 | NPC1 (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL18952487 | 0.73 | S1PR4 (0.62) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL3024027 | 0.73 | S1PR4 (0.64) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL187354 | 0.73 | NPC1 (0.64) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL18952532 | 0.71 | NPC1 (0.58) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL30253292 | 0.68 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3072548 | 0.68 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13603749 | 0.68 | PTGS2 (0.53) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638514-B2 | Agriculture | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-7638514-B2 | Agriculture | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-20070142229-A1 | Pesticidally active phenol derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-06-21 | — | — | US | disclosed |
| US-20070142229-A1 | Pesticidally active phenol derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142229-A1 | Pesticidally active phenol derivatives | DDT, QSOX1, CHRM1 | ALDH1A1 2993/4885MAPT 2257/4885MEN1 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.