SCHEMBL13610368

SCHEMBL13610368

F[Si](F)(c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.50
ALDH1A1 P00352 4/20 0.38
ALOX15 P16050 2/20 0.38
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 1/20 0.35
CA2 P00918 4/20 0.34
CA1 P00915 3/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
TSHR P16473 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
OGG1 O15527 1/20 0.32
GSK3B P49841 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1B1 Q16678 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL697060 0.73 CYP2A6 (0.57) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL17937682 0.71 CYP2A6 (0.53) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL703156 0.71 ESR1 (0.40) CYP2A6ALDH1A1MAPK1TDP1CA2
SCHEMBL18508 0.71
SCHEMBL1538702 0.69 ACHE (0.50) ALDH1A1TDP1CA2CA1CA5A
SCHEMBL8915096 0.69 CYP2A6 (0.50) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL570229 0.69 CYP2A6 (0.50) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL4839303 0.69 CYP2A6 (0.50) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL11419129 0.69 CYP2A6 (0.50) CYP2A6ALDH1A1ALOX15MAPK1TDP1
SCHEMBL13429477 0.69 CYP2A6 (0.50) CYP2A6ALDH1A1ALOX15MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615300-B2 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology The Board of Regents University and Community College System of Nevada on Behalf of the University of Nevada (US) 2009-11-10 US disclosed
US-7615300-B2 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology The Board of Regents University and Community College System of Nevada on Behalf of the University of Nevada (US) 2009-11-10 US disclosed
US-20070048579-A1 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology Board of Regents University and Community College System of Nevada 2007-03-01 US disclosed
US-20070048579-A1 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology Board of Regents University and Community College System of Nevada 2007-03-01 US disclosed