Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2625484 | 0.79 | P2RX7 (0.56) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL13543163 | 0.79 | KDM4E (0.42) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| 2-Mercaptonicotinic Acid SCHEMBL29181672 | 0.79 | KDM4E (0.61) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL27951997 | 0.79 | KDM4E (0.45) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL13542934 | 0.78 | NAPRT (0.61) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL8828593 | 0.78 | LMNA (0.61) | TDP1ALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL13543168 | 0.78 | NAPRT (0.61) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL28555960 | 0.77 | POLB (0.44) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| 2-Mercaptonicotinic Acid SCHEMBL3070055 | 0.77 | KDM4E (0.59) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| 2-Mercaptonicotinic Acid SCHEMBL29382089 | 0.76 | KDM4E (0.63) | KDM4ETDP1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | ADCYAP1R1, VIPR2, ADCY2 | KDM4E 2974/4885TDP1 4059/4885ALDH1A1 2368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.