Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623803 | 0.84 | HCAR2 (0.45) | HCAR2ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL4299723 | 0.82 | BCHE (0.43) | HCAR2ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL4252915 | 0.80 | HCAR2 (0.46) | HCAR2ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL16113553 | 0.78 | HCAR2 (0.52) | HCAR2ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL21552094 | 0.77 | TMPRSS15 (0.58) | HCAR2ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL24035968 | 0.74 | MAPK14 (0.42) | HCAR2FFAR2MAPK14NPC1CYP1A2 | |
| SCHEMBL14047607 | 0.74 | ATG4B (0.39) | HCAR2SMN1; SMN2KDM4EFFAR2MAPK14 | |
| SCHEMBL25409454 | 0.74 | TMPRSS15 (0.59) | HCAR2ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL4249606 | 0.73 | HCAR2 (0.41) | HCAR2ALDH1A1KDM4EFFAR2MAPK14 | |
| SCHEMBL4256153 | 0.72 | RAB9A (0.65) | HCAR2ALDH1A1SMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | ADCYAP1R1, VIPR2, ADCY2 | HCAR2 58/4885ALDH1A1 2368/4885SMN1; SMN2 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.