SCHEMBL13611340

SCHEMBL13611340

CCC(=O)OCC(=O)Nc1ccc(OC(C)C(=O)OCCOC(=O)C(C)Oc2ccc(NC(=O)COC(=O)CC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
POLB P06746 1/20 0.51
KLK7 P49862 3/20 0.49
GAA P10253 1/20 0.48
EPHX2 P34913 2/20 0.47
ATM Q13315 2/20 0.46
MAPK1 P28482 1/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13611338 0.80 CYP1A2 (0.58) KMT2APOLBKLK7GAAATM
SCHEMBL13611343 0.78 KLK7 (0.47) KMT2APOLBKLK7GAAATM
SCHEMBL13611345 0.76 KLK7 (0.51) KMT2AKLK7GAAATMMAPK1
SCHEMBL13611339 0.76 MAPT (0.59) KMT2AGAAATMMAPK1MAPT
SCHEMBL13611342 0.76 KLK7 (0.53) KMT2APOLBKLK7GAAATM
SCHEMBL16270241 0.75 KMT2A (0.52) KMT2AGAAEPHX2MAPTMEN1
SCHEMBL830848 0.75 KMT2A (0.52) KMT2AGAAEPHX2MAPK1MAPT
SCHEMBL10983201 0.74 KLK7 (0.61) KMT2APOLBKLK7GAAMAPK1
SCHEMBL13611347 0.74 ATM (0.44) KMT2APOLBKLK7GAAATM
SCHEMBL13624512 0.74 ATM (0.44) KMT2APOLBKLK7GAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367747-B2 Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2013-02-05 US disclosed
US-8309132-B2 Bioabsorbable polyesteramides and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2012-11-13 US disclosed
US-20090292029-A1 BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF BEZWADA BIOMEDICAL, L.L.C (US) 2009-11-26 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 KMT2A 1362/4885POLB 4656/4885KLK7 1948/4885
US-20090292029-A1 BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF PUF60, PFAS, UROD KMT2A 3235/4885POLB 2889/4885KLK7 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.