Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KLK7 | P49862 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611347 | 1.00 | ATM (0.44) | ATMMAPK1GAAPKMMEN1 | |
| SCHEMBL13611343 | 0.86 | KLK7 (0.47) | ATMMAPK1GAAMEN1KMT2A | |
| SCHEMBL13611346 | 0.85 | MEN1 (0.45) | ATMMAPK1GAAPKMMEN1 | |
| SCHEMBL13624511 | 0.85 | MEN1 (0.45) | ATMMAPK1GAAPKMMEN1 | |
| SCHEMBL13611339 | 0.80 | MAPT (0.59) | ATMMAPK1GAAPKMMEN1 | |
| SCHEMBL10301413 | 0.77 | KMT2A (0.44) | GAAMEN1KMT2AMAPTHTT | |
| SCHEMBL3438965 | 0.77 | PRSS1 (0.50) | GAAMEN1KMT2ASLC22A2TMPRSS2 | |
| SCHEMBL13611345 | 0.76 | KLK7 (0.51) | ATMMAPK1GAAMEN1KMT2A | |
| SCHEMBL13611342 | 0.76 | KLK7 (0.53) | ATMMAPK1GAAMEN1KMT2A | |
| SCHEMBL13611340 | 0.74 | KMT2A (0.52) | ATMMAPK1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309132-B2 | Bioabsorbable polyesteramides and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2012-11-13 | — | — | US | disclosed |
| US-20090285896-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285896-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | PAICS, UROD, PUF60 | ATM 3979/4885MAPK1 4260/4885GAA 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.