SCHEMBL13611342

SCHEMBL13611342

CCC(=O)OCC(=O)Nc1ccc(OC(=O)COCC(=O)Oc2ccc(NC(=O)COC(=O)CC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 5/20 0.53
GAA P10253 2/20 0.52
RAB9A P51151 3/20 0.51
LMNA P02545 1/20 0.51
HTT P42858 1/20 0.51
SIRT5 Q9NXA8 1/20 0.47
MAPT P10636 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPK1 P28482 1/20 0.46
ATM Q13315 1/20 0.46
ALDH1A1 P00352 2/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13611345 0.94 KLK7 (0.51) KLK7GAARAB9ALMNAHTT
SCHEMBL13624511 0.87 MEN1 (0.45) KLK7GAARAB9ALMNAHTT
SCHEMBL13611346 0.87 MEN1 (0.45) KLK7GAARAB9ALMNAHTT
SCHEMBL13611343 0.84 KLK7 (0.47) KLK7GAARAB9ALMNAHTT
SCHEMBL10713248 0.80 RAB9A (0.63) GAARAB9ALMNAHTTMAPT
SCHEMBL13611338 0.79 CYP1A2 (0.58) KLK7GAAHTTSIRT5MAPT
SCHEMBL10983201 0.79 KLK7 (0.61) KLK7GAARAB9AHTTMAPT
SCHEMBL13611340 0.76 KMT2A (0.52) KLK7GAAMAPTMEN1KMT2A
SCHEMBL13611347 0.76 ATM (0.44) KLK7GAARAB9ALMNAHTT
SCHEMBL13624512 0.76 ATM (0.44) KLK7GAARAB9ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130078300-A1 BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2013-03-28 US disclosed
US-20130035402-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2013-02-07 US disclosed
US-8367747-B2 Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2013-02-05 US disclosed
US-8309132-B2 Bioabsorbable polyesteramides and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2012-11-13 US disclosed
US-20090292029-A1 BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF BEZWADA BIOMEDICAL, L.L.C (US) 2009-11-26 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 KLK7 1948/4885GAA 935/4885RAB9A 2810/4885
US-20090292029-A1 BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF PUF60, PFAS, UROD KLK7 630/4885GAA 64/4885RAB9A 1879/4885
US-20130035402-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 KLK7 1948/4885GAA 935/4885RAB9A 2810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.