SCHEMBL13611339

SCHEMBL13611339

CCC(=O)OCC(=O)Nc1ccc(OCCCCCC(=O)OCCOC(=O)CCCCCOc2ccc(NC(=O)COC(=O)CC)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.59
ATM Q13315 2/20 0.58
MAPK1 P28482 1/20 0.58
HTT P42858 2/20 0.54
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
L3MBTL1 Q9Y468 3/20 0.52
GAA P10253 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.51
PKM P14618 1/20 0.50
TDP1 Q9NUW8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13611338 0.87 CYP1A2 (0.58) MAPTATMMAPK1HTTALDH1A1
SCHEMBL13611346 0.83 MEN1 (0.45) MAPTATMMAPK1HTTALDH1A1
SCHEMBL13624511 0.83 MEN1 (0.45) MAPTATMMAPK1HTTALDH1A1
SCHEMBL13611347 0.80 ATM (0.44) MAPTATMMAPK1HTTALDH1A1
SCHEMBL13624512 0.80 ATM (0.44) MAPTATMMAPK1HTTALDH1A1
SCHEMBL13611341 0.80 RAB9A (0.55) MAPTHTTALDH1A1L3MBTL1GAA
SCHEMBL5468760 0.77 MEN1 (0.55) MAPTATMMAPK1HTTALDH1A1
SCHEMBL16270244 0.77 FAAH (0.50) MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL831684 0.76 HDAC8 (0.60) MAPTHTTALDH1A1MEN1KMT2A
SCHEMBL839432 0.76 LMNA (0.59) HTTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367747-B2 Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2013-02-05 US disclosed
US-8309132-B2 Bioabsorbable polyesteramides and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2012-11-13 US disclosed
US-20090292029-A1 BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF BEZWADA BIOMEDICAL, L.L.C (US) 2009-11-26 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 MAPT 1542/4885ATM 3979/4885MAPK1 4260/4885
US-20090292029-A1 BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF PUF60, PFAS, UROD MAPT 3527/4885ATM 4678/4885MAPK1 4264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.