SCHEMBL13611345

SCHEMBL13611345

CCC(=O)OCC(=O)Nc1ccc(OC(=O)COCCOCC(=O)Oc2ccc(NC(=O)COC(=O)CC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 5/20 0.51
MAPT P10636 2/20 0.50
GAA P10253 1/20 0.50
RAB9A P51151 2/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
ATM Q13315 2/20 0.47
MAPK1 P28482 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SIRT5 Q9NXA8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13611342 0.94 KLK7 (0.53) KLK7MAPTGAARAB9ALMNA
SCHEMBL13611346 0.89 MEN1 (0.45) KLK7MAPTGAARAB9ALMNA
SCHEMBL13624511 0.89 MEN1 (0.45) KLK7MAPTGAARAB9ALMNA
SCHEMBL13611343 0.82 KLK7 (0.47) KLK7MAPTGAARAB9ALMNA
SCHEMBL13611338 0.80 CYP1A2 (0.58) KLK7MAPTGAAHTTATM
SCHEMBL10713248 0.78 RAB9A (0.63) MAPTGAARAB9ALMNAHTT
SCHEMBL13611340 0.76 KMT2A (0.52) KLK7MAPTGAAATMMAPK1
SCHEMBL10983201 0.76 KLK7 (0.61) KLK7MAPTGAARAB9AHTT
SCHEMBL13624512 0.76 ATM (0.44) KLK7MAPTGAARAB9ALMNA
SCHEMBL13611347 0.76 ATM (0.44) KLK7MAPTGAARAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367747-B2 Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2013-02-05 US disclosed
US-20090292029-A1 BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF BEZWADA BIOMEDICAL, L.L.C (US) 2009-11-26 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 KLK7 1948/4885MAPT 1542/4885GAA 935/4885
US-20090292029-A1 BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF PUF60, PFAS, UROD KLK7 630/4885MAPT 3527/4885GAA 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.