Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147801 | 0.95 | ALDH1A1 (0.59) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL8013079 | 0.92 | HSP90AA1 (0.60) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL1685052 | 0.90 | HSP90AA1 (0.64) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL28770005 | 0.90 | HSP90AA1 (0.62) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL1643947 | 0.89 | HDAC3 (0.63) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL27390560 | 0.87 | MAPT (0.64) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL175601 | 0.86 | HSP90AA1 (0.65) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| Water SCHEMBL29155573 | 0.86 | HDAC3 (0.60) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL5932679 | 0.84 | HSP90AA1 (0.70) | MAPTKMT2AMEN1ALDH1A1CES1 | |
| SCHEMBL10481745 | 0.84 | HSP90AA1 (0.70) | MAPTKMT2AMEN1ALDH1A1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557849-A | Method for synthesizing imide compound under induction of NBS and water by visible light | 西南大学 | 2023-01-03 | — | — | CN | disclosed |
| US-20090312344-A1 | ARYLPIPERAZINE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312344-A1 | ARYLPIPERAZINE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | ADRA1D, ADRB1, ADRA1A | MAPT 1842/4885KMT2A 1424/4885MEN1 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.