Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524120 | 0.86 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL28036009 | 0.82 | L3MBTL1 (0.63) | PDPK1L3MBTL1ALDH1A1NPSR1LMNA | |
| SCHEMBL726709 | 0.81 | ALDH1A1 (0.70) | L3MBTL1TRPA1ALDH1A1NPSR1LMNA | |
| SCHEMBL728190 | 0.81 | ALDH1A1 (0.70) | L3MBTL1TRPA1ALDH1A1NPSR1LMNA | |
| SCHEMBL10537598 | 0.78 | PDPK1 (0.54) | PDPK1TRPA1LMNATHRBMEN1 | |
| SCHEMBL11528919 | 0.78 | CYP2C9 (0.50) | PDPK1L3MBTL1TRPA1ALDH1A1NPSR1 | |
| SCHEMBL6825864 | 0.78 | MMP2 (0.57) | NPSR1LMNAHPGDMEN1KMT2A | |
| SCHEMBL27494318 | 0.78 | SERPINH1 (0.46) | L3MBTL1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL3412185 | 0.77 | PDPK1 (0.52) | PDPK1L3MBTL1ALDH1A1NPSR1LMNA | |
| SCHEMBL12285419 | 0.77 | PDPK1 (0.52) | PDPK1L3MBTL1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280483-A1 | Methods for Screening Interleukin-6 (IL-6) Signal Transduction Inhibitors | UNIVERSITY OF TOKYO, THE (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090280483-A1 | Methods for Screening Interleukin-6 (IL-6) Signal Transduction Inhibitors | UNIVERSITY OF TOKYO, THE (JP) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280483-A1 | Methods for Screening Interleukin-6 (IL-6) Signal Transduction Inhibitors | IL6, IL6ST, CASP6 | PDPK1 370/4885L3MBTL1 1152/4885TRPA1 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.