SCHEMBL13615152

SCHEMBL13615152

FC(F)=CCCc1ccccc1F

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.52
IDO1 P14902 2/20 0.44
AOC3 Q16853 1/20 0.43
MPO P05164 4/20 0.42
DAO P14920 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAOB P27338 2/20 0.37
HPGD P15428 1/20 0.37
SLC6A4 P31645 1/20 0.37
LMNA P02545 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28344566 0.79 TAAR1 (0.56) TAAR1IDO1AOC3MPODAO
SCHEMBL13439437 0.78 HSD17B1 (0.36) TAAR1
SCHEMBL10049300 0.76 DPP4 (0.46) HPGDALDH1A1
SCHEMBL10049308 0.76 MTNR1A (0.45) HPGD
SCHEMBL12478612 0.75 TAAR1 (0.56) TAAR1IDO1AOC3MPODAO
SCHEMBL2556909 0.75 TAAR1 (0.56) TAAR1IDO1AOC3MPODAO
SCHEMBL436798 0.75 TAAR1 (0.56) TAAR1IDO1AOC3MPODAO
SCHEMBL7563209 0.75 TAAR1 (0.56) TAAR1IDO1AOC3MPODAO
SCHEMBL29373563 0.75 TAAR1 (0.56) TAAR1IDO1AOC3MPODAO
SCHEMBL8526001 0.75 TAAR1 (0.75) TAAR1IDO1AOC3MPODAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed