Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12330525 | 0.87 | ALDH1A1 (0.56) | MTNR1AMTNR1BALDH1A1NPSR1MAPK1 | |
| SCHEMBL13531977 | 0.85 | RAB9A (0.55) | MTNR1AMTNR1BALDH1A1NPSR1MAPK1 | |
| SCHEMBL14437955 | 0.80 | LMNA (0.48) | ALDH1A1TSHRHDAC8HDAC6LMNA | |
| SCHEMBL31483087 | 0.80 | MTNR1A (0.73) | MTNR1AMTNR1BALDH1A1NPSR1MAPK1 | |
| SCHEMBL807668 | 0.80 | NPC1 (0.69) | MTNR1AMTNR1BALDH1A1MAPK1HSD17B10 | |
| SCHEMBL21567107 | 0.79 | MEN1 (0.45) | ALDH1A1NPSR1MAPK1TSHRHDAC8 | |
| SCHEMBL21099911 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1MAPK1HSD17B10 | |
| SCHEMBL31483051 | 0.76 | SMN1; SMN2 (0.53) | MTNR1AMTNR1BALDH1A1NPSR1MAPK1 | |
| SCHEMBL12833381 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TSHRHDAC8HDAC6LMNA | |
| SCHEMBL1053081 | 0.76 | MTNR1A (0.69) | MTNR1AMTNR1BNPC1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306112-A1 | ANTIVIRAL PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306112-A1 | ANTIVIRAL PROTEASE INHIBITORS | ACE, DNPEP, TMPRSS15 | MTNR1A 4145/4885MTNR1B 4186/4885ALDH1A1 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.