Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720136 | 0.72 | ALDH1A1 (0.59) | POLBALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL5213662 | 0.71 | POLB (0.50) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6475236 | 0.70 | KDM4E (0.49) | POLBALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10675913 | 0.68 | ALDH1A1 (0.49) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6965005 | 0.68 | ALDH1A1 (0.45) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9309478 | 0.68 | ALDH1A1 (0.49) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2004433 | 0.68 | L3MBTL1 (0.45) | POLBALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL23302293 | 0.67 | SMN1; SMN2 (0.58) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7030997 | 0.67 | POLB (0.49) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27519532 | 0.67 | ALDH1A1 (0.49) | POLBALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067638-B2 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090233962-A1 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1911751-A1 | AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233962-A1 | Amide derivative and insecticide containing the same | CYP1A1, CYP4B1, CYP2E1 | POLB 4380/4885ALDH1A1 427/4885SMN1; SMN2 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.