Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13825463 | 0.71 | SIGMAR1 (0.47) | — | |
| SCHEMBL16803092 | 0.67 | CYP11B1 (0.33) | — | |
| SCHEMBL19446728 | 0.67 | TTR (0.33) | TTRALBMEN1KMT2A | |
| SCHEMBL7873304 | 0.67 | GRM5 (0.38) | — | |
| SCHEMBL28775027 | 0.66 | CA2 (0.48) | MEN1KMT2A | |
| SCHEMBL202404 | 0.62 | ALDH1A1 (0.61) | TTRALB | |
| SCHEMBL25881784 | 0.62 | SLC6A2 (0.49) | — | |
| SCHEMBL1069352 | 0.62 | TTR (0.38) | TTRALBMEN1KMT2A | |
| SCHEMBL3192191 | 0.62 | VCAM1 (0.35) | TTRALBMEN1KMT2A | |
| SCHEMBL60145 | 0.61 | TTR (0.50) | TTRALBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742908-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-11 | — | — | EP | disclosed |