Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18460493 | 0.81 | ALDH1A1 (0.34) | ALDH1A1MAPT | |
| SCHEMBL11057743 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HTTMAPT | |
| SCHEMBL11059719 | 0.76 | TDP1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL27900484 | 0.76 | EPHX2 (0.42) | ALDH1A1HTTMAPTSIGMAR1GAA | |
| SCHEMBL30828004 | 0.74 | CES2 (0.37) | CES2CES1HTTSIGMAR1 | |
| SCHEMBL19403477 | 0.74 | CES2 (0.37) | CES2CES1HTTSIGMAR1 | |
| SCHEMBL9760714 | 0.74 | CES2 (0.37) | CES2CES1HTTSIGMAR1 | |
| SCHEMBL779932 | 0.74 | CES2 (0.37) | CES2CES1HTTSIGMAR1 | |
| SCHEMBL7294193 | 0.72 | TSHR (0.43) | ALDH1A1NPSR1EPHX1MAPTMEN1 | |
| SCHEMBL1481192 | 0.69 | LTA4H (0.38) | CES2CES1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138589-A1 | NOVEL CATALYTIC SYSTEMS FOR THE RING-OPENING (CO)POLYMERIZATION OF LACTONES | IPSEN PHARMA S.A.S. (FR) | 2009-11-19 | — | — | WO | disclosed |