Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.34 |
| ▸ | P4HB | P07237 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375271 | 0.85 | GAA (0.38) | MEN1KMT2A | |
| SCHEMBL27593612 | 0.84 | LMNA (0.37) | OPRD1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL3838880 | 0.84 | LMNA (0.37) | OPRD1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL8363717 | 0.80 | CPB2 (0.45) | ALDH1A1 | |
| SCHEMBL3843654 | 0.80 | OPRD1 (0.35) | OPRD1OPRM1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3085673 | 0.79 | ALDH1A1 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL17233692 | 0.78 | KMT2A (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL17525712 | 0.77 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL4622374 | 0.77 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL12199033 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311488-B1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | PFIZER LTD (GB) | 2009-11-04 | — | — | EP | disclosed |