SCHEMBL1361855

SCHEMBL1361855

CCCCCCCCCCC(=O)OC(=N)CCC(=O)OC(=O)CCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.52
LMNA P02545 2/20 0.48
PAM P19021 2/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.46
MAPK1 P28482 1/20 0.46
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
TSHR P16473 4/20 0.44
HSP90AA1 P07900 1/20 0.44
PPARG P37231 4/20 0.43
PPARD Q03181 4/20 0.43
PPARA Q07869 4/20 0.43
GPR84 Q9NQS5 3/20 0.43
HDAC11 Q96DB2 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
TLR2 O60603 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10949517 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL6889455 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL11639759 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL5070013 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL9565427 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL6535867 0.98 DGKA (0.48) DGKALMNAPAMALDH1A1MAPT
SCHEMBL6526444 0.92 ALDH1A1 (0.50) DGKALMNAPAMALDH1A1MAPT
SCHEMBL28181086 0.90 DGKA (0.53) DGKALMNAPAMALDH1A1MAPT
SCHEMBL2779344 0.90 CNR2 (0.55) DGKALMNAMAPTPPARGPPARD
SCHEMBL28199038 0.88 DGKA (0.50) DGKALMNAPAMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115014886-A Method for preparing measurement sample, method for analyzing measurement sample, reagent, and kit 希森美康株式会社 2022-09-06 CN claimed
WO-2020004535-A1 SENSOR CHIP FOR HIGH-SENSITIVITY DETECTION OF CELLS, ETC. 株式会社堀場製作所 2020-01-02 WO claimed
CN-111936837-B QMAX assay and use 上海宜晟生物科技有限公司 2024-06-07 CN disclosed
US-11940382-B2 Assay with amplification ESSENLIX CORPORATION (US) 2024-03-26 US disclosed
US-11892746-B1 Super system on chip MAZED MOHAMMAD A (US) 2024-02-06 US disclosed
US-11885887-B1 Imaging subsystem MAZED MOHAMMAD A (US) 2024-01-30 US disclosed
US-11320588-B1 Super system on chip MAZED MOHAMMAD A (US) 2022-05-03 US disclosed
CN-111936837-A QMAX determination and uses ESSENLIX公司 2020-11-13 CN disclosed
US-20200319176-A1 QMAX ASSAYS AND APPLICATIONS ESSENLIX CORPORATION (US) 2020-10-08 US disclosed
US-20200225161-A1 ASSAY WITH AMPLIFICATION ESSENLIX CORPORATION (US) 2020-07-16 US disclosed
US-10656149-B2 Analyte detection enhancement by targeted immobilization, surface amplification, and pixelated reading and analysis THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2020-05-19 US disclosed
WO-2013154770-A1 ULTRA-SENSITIVE SENSOR THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2013-10-17 WO disclosed
US-20130171712-A1 CULTURE METHOD AND CULTURE DEVICE UNIVERSITY OF TSUKUBA (JP) 2013-07-04 US disclosed
CN-102307885-A Method for introducing functional groups to the surface of a substance NAT UNIV KANGNUNG WONJU 2012-01-04 CN disclosed
US-8067053-B2 Method for selective immobilization of macromolecules on self assembled monolayer surfaces BATTELLE MEMORIAL INSTITUTE (US) 2011-11-29 US disclosed
US-20110082279-A1 Chemiluminescent Compounds GEN-PROBE INCORPORATED (US) 2011-04-07 US disclosed
US-20100285514-A1 ELECTROCHEMICAL BIOSENSOR PURDUE RESEARCH FOUNDATION 2010-11-11 US disclosed
EP-1658503-B1 CHEMILUMINESCENT COMPOUNDS MOLECULAR LIGHT TECH RES LTD (GB) 2009-11-18 EP disclosed
US-20090280264-A1 Method for selective immobilization of macromolecules on self assembled monolayer surfaces U.S. DEPARTMENT OF ENERGY 2009-11-12 US disclosed
US-20070166759-A1 Chemiluminescent compounds GEN-PROBE CARDIFF, LTD. (GB) 2007-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070166759-A1 Chemiluminescent compounds CBR3, CBR1, LTC4S DGKA 4102/4885LMNA 202/4885PAM 753/4885
US-20110082279-A1 Chemiluminescent Compounds CBR3, LTC4S, CBR1 DGKA 4229/4885LMNA 131/4885PAM 629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.