SCHEMBL6889455

SCHEMBL6889455

CCCCCCCC(=O)OC(=N)CCC(=O)OC(=O)CCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.52
LMNA P02545 2/20 0.48
PAM P19021 2/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.46
MAPK1 P28482 1/20 0.46
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
TSHR P16473 4/20 0.44
HSP90AA1 P07900 1/20 0.44
PPARG P37231 4/20 0.43
PPARD Q03181 4/20 0.43
PPARA Q07869 4/20 0.43
GPR84 Q9NQS5 3/20 0.43
HDAC11 Q96DB2 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
TLR2 O60603 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10949517 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL1361855 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL11639759 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL5070013 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL9565427 1.00 DGKA (0.52) DGKALMNAPAMALDH1A1MAPT
SCHEMBL6535867 0.98 DGKA (0.48) DGKALMNAPAMALDH1A1MAPT
SCHEMBL6526444 0.92 ALDH1A1 (0.50) DGKALMNAPAMALDH1A1MAPT
SCHEMBL28181086 0.90 DGKA (0.53) DGKALMNAPAMALDH1A1MAPT
SCHEMBL2779344 0.90 CNR2 (0.55) DGKALMNAMAPTPPARGPPARD
SCHEMBL28199038 0.88 DGKA (0.50) DGKALMNAPAMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111217791-B Ibrutin intermediate and preparation method thereof 广东东阳光药业股份有限公司 2024-02-02 CN claimed
CN-115014886-A Method for preparing measurement sample, method for analyzing measurement sample, reagent, and kit 希森美康株式会社 2022-09-06 CN claimed
CN-111217791-A Ibrustat intermediate and preparation method thereof 广东东阳光药业有限公司 2020-06-02 CN claimed
WO-2020004535-A1 SENSOR CHIP FOR HIGH-SENSITIVITY DETECTION OF CELLS, ETC. 株式会社堀場製作所 2020-01-02 WO claimed
CN-111217791-B Ibrutin intermediate and preparation method thereof 广东东阳光药业股份有限公司 2024-02-02 CN disclosed
CN-113967267-B Endoplasmic reticulum targeting of fatty acid modified albumin and uses thereof 四川大学 2022-10-25 CN disclosed
CN-113967267-A Endoplasmic reticulum targeting of fatty acid modified albumin and uses thereof 四川大学 2022-01-25 CN disclosed
CN-111217791-A Ibrustat intermediate and preparation method thereof 广东东阳光药业有限公司 2020-06-02 CN disclosed
US-20200038427-A1 CYCLIC NUCLEIC ACID MOLECULE HAVING GENE EXPRESSION CONTROL FUNCTION BONAC CORPORATION (JP) 2020-02-06 US disclosed
EP-3604528-A1 CYCLIC NUCLEIC ACID MOLECULE HAVING GENE EXPRESSION CONTROL FUNCTION Bonac Corporation (JP) 2020-02-05 EP disclosed
WO-2020004535-A1 SENSOR CHIP FOR HIGH-SENSITIVITY DETECTION OF CELLS, ETC. 株式会社堀場製作所 2020-01-02 WO disclosed
EP-1413886-A1 Sensor surface INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM ( IMEC) (BE) 2004-04-28 EP disclosed
US-20040018532-A1 Sensitive quantitative analysis; minaturization INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) 2004-01-29 US disclosed
EP-1369692-A2 Sensor surface Interuniversitaire Microelectronica Centrum vzw ( IMEC) (BE) 2003-12-10 EP disclosed
EP-1100520-A4 NOVEL FLUORESCENCE DYES AND THEIR APPLICATIONS FOR WHOLE CELL FLUORESCENCE SCREENING ASSAYS FOR CASPASES, PEPTIDASES, PROTEASES AND OTHER ENZYMES AND THE USE THEREOF CYTOVIA INC (US) 2002-07-17 EP disclosed
EP-1100520-A1 NOVEL FLUORESCENCE DYES AND THEIR APPLICATIONS FOR WHOLE CELL FLUORESCENCE SCREENING ASSAYS FOR CASPASES, PEPTIDASES, PROTEASES AND OTHER ENZYMES AND THE USE THEREOF Cytovia, Inc. (US) 2001-05-23 EP disclosed
WO-2000004914-A1 NOVEL FLUORESCENCE DYES AND THEIR APPLICATIONS FOR WHOLE CELL FLUORESCENCE SCREENING ASSAYS FOR CASPASES, PEPTIDASES, PROTEASES AND OTHER ENZYMES AND THE USE THEREOF CYTOVIA, INC. (US) 2000-02-03 WO disclosed
US-4126628-A BASIC CATALYST CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) 1978-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200038427-A1 CYCLIC NUCLEIC ACID MOLECULE HAVING GENE EXPRESSION CONTROL FUNCTION RNMT, RNGTT, SRRT DGKA 2298/4885LMNA 1101/4885PAM 3133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.