SCHEMBL6535867

SCHEMBL6535867

CCCCCC(=O)OC(=N)CCC(=O)OC(=O)CCCCC

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.48
ALDH1A1 P00352 2/20 0.48
LMNA P02545 3/20 0.46
PAM P19021 2/20 0.44
CES2 O00748 4/20 0.43
CES1 P23141 4/20 0.43
MAPT P10636 2/20 0.43
MAPK1 P28482 1/20 0.43
TSHR P16473 1/20 0.42
AKR1B1 P15121 1/20 0.41
HSP90AA1 P07900 1/20 0.41
DNM1 Q05193 1/20 0.41
POLB P06746 1/20 0.41
POLA1 P09884 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5070013 0.98 DGKA (0.52) DGKAALDH1A1LMNAPAMCES2
SCHEMBL6889455 0.98 DGKA (0.52) DGKAALDH1A1LMNAPAMCES2
SCHEMBL11639759 0.98 DGKA (0.52) DGKAALDH1A1LMNAPAMCES2
SCHEMBL1361855 0.98 DGKA (0.52) DGKAALDH1A1LMNAPAMCES2
SCHEMBL10949517 0.98 DGKA (0.52) DGKAALDH1A1LMNAPAMCES2
SCHEMBL9565427 0.98 DGKA (0.52) DGKAALDH1A1LMNAPAMCES2
SCHEMBL6526444 0.94 ALDH1A1 (0.50) DGKAALDH1A1LMNAPAMCES2
SCHEMBL28161543 0.90 DGKA (0.50) DGKAALDH1A1LMNAPAMCES2
SCHEMBL2779344 0.88 CNR2 (0.55) DGKALMNAMAPTPOLB
SCHEMBL28181086 0.88 DGKA (0.53) DGKAALDH1A1LMNAPAMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117731826-A Platelet-rich plasma hydrogel with growth factors slowly released and preparation method and application thereof 武汉理工大学 2024-03-22 CN claimed
CN-116987373-A Radiation protection hydrogel and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2023-11-03 CN claimed
CN-116875024-A Hydrogel with X-ray visibility and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2023-10-13 CN claimed
CN-115014886-A Method for preparing measurement sample, method for analyzing measurement sample, reagent, and kit 希森美康株式会社 2022-09-06 CN claimed
EP-4104853-B1 ARGININE DEIMINASE WITH REDUCED CROSS-REACTIVITY TOWARD ADI - PEG 20 ANTIBODIES FOR CANCER TREATMENT POLARIS GROUP (KY) 2026-05-06 EP disclosed
EP-3609527-B1 PROTEIN CONJUGATES POLARIS GROUP (KY) 2025-07-30 EP disclosed
US-12274737-B2 PEGylated recombinant human growth hormone compounds ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S (DK) 2025-04-15 US disclosed
CN-119700941-A Long acting interleukin-15 receptor agonists and related immunotherapeutic compositions and methods 尼克塔治疗公司 2025-03-28 CN disclosed
US-20240424115-A1 LONG-ACTING INTERLEUKIN-15 RECEPTOR AGONISTS AND RELATED IMMUNOTHERAPEUTIC COMPOSITIONS AND METHODS NEKTAR THERAPEUTICS (US) 2024-12-26 US disclosed
CN-113144178-B Methods and compositions for modulating the immune system using arginase I 康达医药科技有限公司 2024-10-18 CN disclosed
WO-2024196783-A1 BIOENGINEERED COLON-SPECIFIC IMMUNE NICHE FOR THE TREATMENT OF ULCERATIVE COLITIS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-09-26 WO disclosed
US-12036283-B2 Long-acting interleukin-15 receptor agonists and related immunotherapeutic compositions and methods NEKTAR THERAPEUTICS (US) 2024-07-16 US disclosed
CN-106456723-B Methods and compositions for modulating the immune system using arginase I 康达医药科技有限公司 2021-03-09 CN disclosed
CN-111032850-A Oligomeric particle reagents and methods of use thereof 朱诺治疗学有限公司 2020-04-17 CN disclosed
WO-2020004535-A1 SENSOR CHIP FOR HIGH-SENSITIVITY DETECTION OF CELLS, ETC. 株式会社堀場製作所 2020-01-02 WO disclosed
CN-106456723-A Methods and compositions for modulating the immune system using arginase I 康达医药科技有限公司 2017-02-22 CN disclosed
EP-1352072-A4 NUCLEIC ACID DELIVERY FORMULATIONS ZYCOS INC (US) 2004-09-01 EP disclosed
US-20040147466-A1 Nucleic acid delivery formulations MGI PHARMA BIOLOGICS, INC. 2004-07-29 US disclosed
EP-1352072-A2 NUCLEIC ACID DELIVERY FORMULATIONS Zycos Inc. (US) 2003-10-15 EP disclosed
WO-2002057424-A2 NUCLEIC ACID DELIVERY FORMULATIONS ZYCOS INC. (US) 2002-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12274737-B2 PEGylated recombinant human growth hormone compounds GHRHR, GHITM, GHSR DGKA 1127/4885ALDH1A1 4398/4885LMNA 1535/4885
US-20240424115-A1 LONG-ACTING INTERLEUKIN-15 RECEPTOR AGONISTS AND RELATED IMMUNOTHERAPEUTIC COMPOSITIONS AND METHODS IL15RA, IL15, IL2RA DGKA 504/4885ALDH1A1 4392/4885LMNA 3083/4885
US-12036283-B2 Long-acting interleukin-15 receptor agonists and related immunotherapeutic compositions and methods IL15RA, IL15, IL2RA DGKA 504/4885ALDH1A1 4392/4885LMNA 3083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.