SCHEMBL13618704

SCHEMBL13618704

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nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CYP2D6 P10635 1/20 0.45
KMT2A Q03164 2/20 0.43
CTSK P43235 8/20 0.42
CTSS P25774 4/20 0.42
CA12 O43570 1/20 0.42
CA14 Q9ULX7 1/20 0.42
GLS O94925 1/20 0.42
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
TRPA1 O75762 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31503278 1.00 CA1 (0.50) CA1CA2CA7CYP2D6KMT2A
SCHEMBL8906230 0.83 CA14 (0.33) CA1CA2CA7CA12CA14
SCHEMBL8907625 0.83 CA14 (0.33) CA1CA2CA7CA12CA14
SCHEMBL19318523 0.83 CA14 (0.33) CA1CA2CA7CA12CA14
SCHEMBL19750452 0.81 CA1 (0.49) CA1CA2CA7CYP2D6KMT2A
SCHEMBL23607312 0.81 CA1 (0.52) CA1CA2CA7CYP2D6KMT2A
SCHEMBL1371004 0.81 CA1 (0.52) CA1CA2CA7CYP2D6KMT2A
SCHEMBL1369240 0.81 CA1 (0.52) CA1CA2CA7CYP2D6KMT2A
SCHEMBL148100 0.81 CA1 (0.52) CA1CA2CA7CYP2D6KMT2A
SCHEMBL23849248 0.81 CA1 (0.52) CA1CA2CA7CYP2D6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11786605-B2 Site specific antibody-drug conjugates with peptide-containing linkers MERSANA THERAPEUTICS, INC. (US) 2023-10-17 US disclosed
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES ASANA BIOSCIENCES, LLC 2023-06-15 US disclosed
US-20230043447-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2023-02-09 US disclosed
US-20230021500-A1 CYSTEINE ENGINEERED ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS MERSANA THERAPEUTICS, INC. 2023-01-26 US disclosed
US-11135307-B2 Peptide-containing linkers for antibody-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2021-10-05 US disclosed
US-20210220477-A1 SITE SPECIFIC ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS MERSANA THERAPEUTICS, INC. 2021-07-22 US disclosed
US-20210106690-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2021-04-15 US disclosed
US-10772971-B2 Methods of producing drug-carrying polymer scaffolds and protein-polymer-drug conjugates Mersana Therpeutics, Inc. (US) 2020-09-15 US disclosed
US-10603386-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2020-03-31 US disclosed
US-20190241649-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2019-08-08 US disclosed
US-20180154018-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2018-06-07 US disclosed
US-20180140716-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2018-05-24 US disclosed
US-9943609-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2018-04-17 US disclosed
US-9872918-B2 Hydroxyl-polymer-drug-protein conjugates MERSANA THERAPEUTICS, INC. (US) 2018-01-23 US disclosed
US-9849191-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2017-12-26 US disclosed
US-20170348424-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2017-12-07 US disclosed
US-9808528-B2 Protein-polymer-drug conjugates and methods of using same MERSANA THERAPEUTICS, INC. (US) 2017-11-07 US disclosed
US-9770519-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2017-09-26 US disclosed
US-20170119896-A1 TERMINALLY MODIFIED POLYMERS AND CONJUGATES THEREOF MERSANA THERAPEUTICS, INC. 2017-05-04 US disclosed
US-20090281062-A1 NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF EVOTEC LTD. (GB) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190241649-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, STAMBP, TSPO CA1 3384/4885CA2 3833/4885CA7 3439/4885
US-11135307-B2 Peptide-containing linkers for antibody-drug conjugates CD2BP2, DNPEP, LNPEP CA1 1736/4885CA2 4361/4885CA7 2306/4885
US-20170348424-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, CLTB, BRAP CA1 4702/4885CA2 4687/4885CA7 4332/4885
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, STAMBP, TSPO CA1 3384/4885CA2 3833/4885CA7 3439/4885
US-20180140716-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, STAMBP, TSPO CA1 3384/4885CA2 3833/4885CA7 3439/4885
US-10772971-B2 Methods of producing drug-carrying polymer scaffolds and protein-polymer-drug conjugates PBRM1, BRAP, STAMBP CA1 3810/4885CA2 4131/4885CA7 3418/4885
US-20230021500-A1 CYSTEINE ENGINEERED ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS LNPEP, DNPEP, QPCT CA1 463/4885CA2 3245/4885CA7 1439/4885
US-20230043447-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES CD2BP2, DNPEP, LNPEP CA1 1736/4885CA2 4361/4885CA7 2306/4885
US-20090281062-A1 NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF NOXO1, TNNI3, HAO2 CA1 706/4885CA2 646/4885CA7 772/4885
US-11786605-B2 Site specific antibody-drug conjugates with peptide-containing linkers CD2BP2, DNPEP, LNPEP CA1 1306/4885CA2 3825/4885CA7 2015/4885
US-20210106690-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, CLTB, BRAP CA1 4787/4885CA2 4742/4885CA7 4307/4885
US-10603386-B2 Protein-polymer-drug conjugates PBRM1, CLTB, BRAP CA1 4800/4885CA2 4745/4885CA7 4324/4885
US-20210220477-A1 SITE SPECIFIC ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS CD2BP2, DNPEP, LNPEP CA1 1306/4885CA2 3825/4885CA7 2015/4885
US-20180154018-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES CD2BP2, DNPEP, LNPEP CA1 1736/4885CA2 4361/4885CA7 2306/4885
US-20170119896-A1 TERMINALLY MODIFIED POLYMERS AND CONJUGATES THEREOF MALT1, ALG1, PRMT3 CA1 2585/4885CA2 4349/4885CA7 2156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.