Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14568800 | 0.81 | PPP5C (0.38) | CA12CA1CA2CA9PPP5C | |
| SCHEMBL19789660 | 0.80 | LMNA (0.41) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL12221621 | 0.79 | HSD17B10 (0.44) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL13620083 | 0.77 | HSD17B10 (0.39) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL16379712 | 0.71 | CA12 (0.41) | CA12CA1CA2CA9PPP5C | |
| SCHEMBL10056659 | 0.70 | THRB (0.53) | CA12CA1CA2CA9HSD17B10 | |
| SCHEMBL13019176 | 0.70 | THRB (0.53) | CA12CA1CA2CA9HSD17B10 | |
| SCHEMBL14568665 | 0.70 | ALDH1A1 (0.36) | CA12CA1CA2CA9PPP5C | |
| SCHEMBL16127014 | 0.69 | ALDH1A1 (0.41) | PPP5CALDH1A1 | |
| SCHEMBL14568802 | 0.69 | PPP5C (0.39) | PPP5CALDH1A1HSD17B10THRBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132832-A2 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-11-05 | — | — | WO | disclosed |