SCHEMBL13620116

SCHEMBL13620116

COc1ccc(C(c2ccc(OC(C)=O)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
BACE1 P56817 2/20 0.45
HSD11B1 P28845 1/20 0.44
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
CYP1A1 P04798 2/20 0.42
CYP1B1 Q16678 2/20 0.42
ELANE P08246 1/20 0.42
PDK1 Q15118 1/20 0.42
PDK2 Q15119 1/20 0.42
PDK3 Q15120 1/20 0.42
PDK4 Q16654 1/20 0.42
MAOB P27338 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 2/20 0.41
F2 P00734 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6939142 0.93 LMNA (0.53) LMNABACE1MAPTPOLBPKM
SCHEMBL20312049 0.84 ELANE (0.47) LMNAHSD11B1MAPTCYP1A1CYP1B1
SCHEMBL2616610 0.84 CA1 (0.52) HSD11B1MAPTPDK1PDK2PDK3
SCHEMBL10112762 0.84 CA1 (0.52) HSD11B1MAPTPDK1PDK2PDK3
SCHEMBL13620115 0.83 BACE1 (0.40) LMNABACE1HSD11B1MAPTPOLB
SCHEMBL17124304 0.83 LMNA (0.42) LMNAHSD11B1MAPTPDK1PDK2
SCHEMBL18219808 0.82 LMNA (0.53) LMNABACE1MAPTPOLBPKM
SCHEMBL15957711 0.82 HSD11B1 (0.39) LMNAHSD11B1MAPTCYP1A1CYP1B1
SCHEMBL12762422 0.82 KMT2A (0.50) LMNAMAPTCYP1A1CYP1B1MAOB
SCHEMBL1871227 0.82 LMNA (0.67) LMNABACE1MAPTPOLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626701-B1 FLUORINATED CARBONATE DERIVATIVE PRODUCTION METHOD UNIV KOBE NAT UNIV CORP (JP) 2024-07-17 EP disclosed
US-11167259-B2 Fluorinated carbonate derivative production method NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2021-11-09 US disclosed
US-20200122114-A1 FLUORINATED CARBONATE DERIVATIVE PRODUCTION METHOD NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2020-04-23 US disclosed
US-20180059558-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
US-9864284-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-01-09 US disclosed
US-9766561-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-19 US disclosed
US-9753385-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-05 US disclosed
US-9684277-B2 Process cartridge and image-forming method CANON KABUSHIKI KAISHA (JP) 2017-06-20 US disclosed
US-9651879-B2 Electrophotographic photosensitive member, method of producing the electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-05-16 US disclosed
US-20170060008-A1 IMAGE FORMING METHOD, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-03-02 US disclosed
US-20140255838-A1 PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-09-11 US disclosed
US-20140205946-A1 METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-07-24 US disclosed
US-20140205940-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-07-24 US disclosed
US-8765335-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-07-01 US disclosed
US-20130040234-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2013-02-14 US disclosed
US-20130029266-A1 METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2013-01-31 US disclosed
US-20130029256-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2013-01-31 US disclosed
US-20090292034-A1 POLYCARBONATE FOAM THE FURUKAWA ELECTRIC CO., LTD. (JP) 2009-11-26 US disclosed
US-7183027-B2 Image forming method FUJI XEROX CO., LTD. (JP) 2007-02-27 US disclosed
US-7160659-B2 Electrophotographic apparatus and process cartridge CANON KABUSHIKI KAISHA (JP) 2007-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11167259-B2 Fluorinated carbonate derivative production method CA4, CA3, CA14 LMNA 2308/4885BACE1 2780/4885HSD11B1 225/4885
US-20200122114-A1 FLUORINATED CARBONATE DERIVATIVE PRODUCTION METHOD CA4, CA3, CA14 LMNA 2308/4885BACE1 2780/4885HSD11B1 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.