SCHEMBL13620526

SCHEMBL13620526

COc1ccc(/C=[N+](/C)[O-])cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.53
ALDH1A1 P00352 3/20 0.50
CYP2A6 P11509 1/20 0.50
KDM4E B2RXH2 4/20 0.48
CYP3A4 P08684 2/20 0.48
LMNA P02545 2/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
TRPA1 O75762 1/20 0.47
RELA Q04206 1/20 0.47
CYP1A2 P05177 3/20 0.45
CYP1A1 P04798 3/20 0.45
CYP1B1 Q16678 3/20 0.45
ESR1 P03372 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9632582 1.00 FBP1 (0.53) FBP1ALDH1A1CYP2A6KDM4ECYP3A4
SCHEMBL2152818 0.78 FBP1 (0.49) FBP1ALDH1A1CYP2A6KDM4ECYP3A4
SCHEMBL30128650 0.78 FBP1 (0.49) FBP1ALDH1A1CYP2A6KDM4ECYP3A4
SCHEMBL28609695 0.75 ALDH1A1 (0.64) FBP1ALDH1A1CYP2A6KDM4ECYP3A4
SCHEMBL9633590 0.75 ALDH1A1 (0.64) FBP1ALDH1A1CYP2A6KDM4ECYP3A4
SCHEMBL9631776 0.75 FBP1 (0.48) FBP1CYP2A6KDM4ECA1RELA
SCHEMBL9632571 0.74 FBP1 (0.53) FBP1ALDH1A1KDM4ECYP3A4LMNA
SCHEMBL13100474 0.74 NR1I2 (0.46) ALDH1A1CYP3A4LMNAPTGS2CYP19A1
SCHEMBL9631799 0.73 EGFR (0.47) FBP1ALDH1A1KDM4ECYP3A4LMNA
SCHEMBL11754100 0.73 ALDH1A1 (0.50) FBP1ALDH1A1CYP2A6LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009136920-A1 MULTIFUNCTIONAL NITRONES IN NON-RADICAL SYSTEMS HENKEL CORPORATION (US) 2009-11-12 WO disclosed