SCHEMBL9631776

SCHEMBL9631776

Cc1ccc(C=[N+](C)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.48
CYP2A6 P11509 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ACHE P22303 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
NFE2L2 Q16236 3/20 0.39
RELA Q04206 1/20 0.37
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
RECQL P46063 1/20 0.37
MDM2 Q00987 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CA1 P00915 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13100477 0.89 L3MBTL1 (0.43) FBP1L3MBTL1NPC1HSD17B10TDP1
SCHEMBL9631799 0.78 EGFR (0.47) FBP1RAB9ANPC1SMN1; SMN2HSD17B10
SCHEMBL11754100 0.78 ALDH1A1 (0.50) FBP1CYP2A6L3MBTL1NPC1HSD17B10
SCHEMBL1404289 0.77 G6PD (0.47) FBP1L3MBTL1RAB9ANPC1TDP1
SCHEMBL22575907 0.77 G6PD (0.47) FBP1L3MBTL1RAB9ANPC1TDP1
SCHEMBL10448311 0.77 G6PD (0.47) FBP1L3MBTL1RAB9ANPC1TDP1
Hydrochloric Acid SCHEMBL5256861 0.77 CYP2A6 (0.46) FBP1CYP2A6L3MBTL1RAB9ANPC1
SCHEMBL11404254 0.76 ALDH1A1 (0.53) FBP1CYP2A6RAB9ANPC1SMN1; SMN2
SCHEMBL15216491 0.75 FBP1 (0.44) FBP1CYP2A6L3MBTL1RAB9ANPC1
SCHEMBL11752668 0.75 APP (0.55) FBP1RAB9ANPC1ACHEHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5106723-A Contrast enhancement layer compositions, alkylnitrones, and use MICROSI, INC. (US) 1992-04-21 US claimed
US-5002993-A Contrast enhancement layer compositions, alkylnitrones, and use MICROSI, INC. (US) 1991-03-26 US claimed
CN-115583970-B Method for preparing alpha- (hydroxyamino) diaryl phosphine oxide from nitrone 华北理工大学 2024-11-26 CN disclosed
CN-115583970-A Method for preparing alpha- (hydroxy amino) diaryl phosphine oxide from nitrone 华北理工大学 2023-01-10 CN disclosed
EP-0254221-B1 CONTRAST ENHANCEMENT LAYER COMPOSITIONS, ALKYLNITRONES, AND USE MicroSi, Inc. (a Delaware corporation) (US) 1992-05-13 EP disclosed
US-5106723-A Contrast enhancement layer compositions, alkylnitrones, and use MICROSI, INC. (US) 1992-04-21 US disclosed
US-5002993-A Contrast enhancement layer compositions, alkylnitrones, and use MICROSI, INC. (US) 1991-03-26 US disclosed
EP-0254221-A2 Contrast enhancement layer compositions, alkylnitrones, and use MicroSi, Inc. (a Delaware corporation) (US) 1988-01-27 EP disclosed