Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100477 | 0.87 | L3MBTL1 (0.43) | FBP1ALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL9631776 | 0.78 | FBP1 (0.48) | FBP1MAPTKDM4ECA1HSD17B10 | |
| SCHEMBL11754100 | 0.76 | ALDH1A1 (0.50) | FBP1ALDH1A1MAPTLMNAHSD17B10 | |
| SCHEMBL14992514 | 0.76 | EGFR (0.42) | EGFRFBP1ALDH5A1ABATAPP | |
| SCHEMBL4712004 | 0.76 | TDP1 (0.43) | EGFRFBP1ALDH5A1ABATAPP | |
| SCHEMBL14993283 | 0.76 | EGFR (0.42) | EGFRFBP1ALDH5A1ABATAPP | |
| SCHEMBL14992517 | 0.76 | EGFR (0.42) | EGFRFBP1ALDH5A1ABATAPP | |
| SCHEMBL14993056 | 0.76 | TDP1 (0.43) | EGFRFBP1ALDH5A1ABATAPP | |
| SCHEMBL14993281 | 0.76 | EGFR (0.42) | EGFRFBP1ALDH5A1ABATAPP | |
| SCHEMBL14993055 | 0.76 | TDP1 (0.43) | EGFRFBP1ALDH5A1ABATAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106723-A | Contrast enhancement layer compositions, alkylnitrones, and use | MICROSI, INC. (US) | 1992-04-21 | — | — | US | claimed |
| US-5002993-A | Contrast enhancement layer compositions, alkylnitrones, and use | MICROSI, INC. (US) | 1991-03-26 | — | — | US | claimed |
| EP-0254221-B1 | CONTRAST ENHANCEMENT LAYER COMPOSITIONS, ALKYLNITRONES, AND USE | MicroSi, Inc. (a Delaware corporation) (US) | 1992-05-13 | — | — | EP | disclosed |
| US-5106723-A | Contrast enhancement layer compositions, alkylnitrones, and use | MICROSI, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5002993-A | Contrast enhancement layer compositions, alkylnitrones, and use | MICROSI, INC. (US) | 1991-03-26 | — | — | US | disclosed |