Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 2/20 | 0.48 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100477 | 0.87 | L3MBTL1 (0.43) | ALDH1A1MAPTNPC1G6PDFBP1 | |
| SCHEMBL9631776 | 0.78 | FBP1 (0.48) | MAPTNPC1FBP1HSD17B10TDP1 | |
| SCHEMBL13461939 | 0.76 | HSD17B10 (0.42) | ALDH1A1MAPTNPC1G6PDFBP1 | |
| SCHEMBL9341341 | 0.76 | NPC1 (0.50) | ALDH1A1MAPTNPC1G6PDFBP1 | |
| SCHEMBL9631799 | 0.76 | EGFR (0.47) | ALDH1A1MAPTNPC1FBP1HSD17B10 | |
| SCHEMBL9341340 | 0.76 | NPC1 (0.50) | ALDH1A1MAPTNPC1G6PDFBP1 | |
| SCHEMBL8039808 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTNPC1G6PDFBP1 | |
| SCHEMBL15216499 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTNPC1G6PDFBP1 | |
| SCHEMBL22575907 | 0.75 | G6PD (0.47) | ALDH1A1MAPTNPC1G6PDFBP1 | |
| SCHEMBL1404289 | 0.75 | G6PD (0.47) | ALDH1A1MAPTNPC1G6PDFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018774-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-04-19 | — | — | US | disclosed |