Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 8/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 5/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620673 | 0.95 | FTO (0.54) | FTOGSTP1MEN1MAPTHTT | |
| SCHEMBL14265156 | 0.88 | FTO (0.47) | FTOGSTP1MEN1MAPTHTT | |
| SCHEMBL13620666 | 0.80 | MEN1 (0.69) | FTOGSTP1MEN1MAPTHTT | |
| SCHEMBL13620743 | 0.79 | FTO (0.57) | FTOGSTP1MEN1MAPTHTT | |
| SCHEMBL29349570 | 0.79 | MAPT (0.66) | FTOGSTP1MEN1MAPTHTT | |
| SCHEMBL1024927 | 0.79 | MAPT (0.66) | FTOGSTP1MEN1MAPTHTT | |
| SCHEMBL20420116 | 0.78 | ALDH1A1 (0.52) | FTOGSTP1MEN1MAPTHTT | |
| SCHEMBL29382186 | 0.78 | ALDH1A1 (0.52) | FTOGSTP1MEN1MAPTHTT | |
| SCHEMBL15274919 | 0.78 | GSTP1 (0.45) | FTOGSTP1MEN1MAPTHTT | |
| SCHEMBL9626406 | 0.75 | FTO (0.81) | FTOMEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204430-B1 | CONJUGATES AND METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE FOR TRANSPORTING MOLECULES VIA BIOLOGICAL MEMBRANES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-04 | — | — | EP | disclosed |