Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | MGMT | P16455 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610708 | 0.93 | MAPT (0.43) | MAPTBLMKMT2APOLBRAD52 | |
| SCHEMBL13622016 | 0.82 | KCNH3 (0.44) | MAPTKMT2AKCNH3L3MBTL1HTR1A | |
| SCHEMBL13752395 | 0.76 | MAPT (0.38) | MAPTBLMKMT2APOLBRAD52 | |
| SCHEMBL28855675 | 0.74 | KAT2B (0.60) | MAPTBLMKMT2APOLBL3MBTL1 | |
| SCHEMBL4610548 | 0.74 | KCNH3 (0.43) | KCNH3L3MBTL1ADRA1DADRA1AADRA1B | |
| SCHEMBL4238515 | 0.74 | MAPT (0.42) | MAPTBLMKMT2APOLBRAD52 | |
| SCHEMBL13743141 | 0.73 | MGMT (0.39) | MAPTKMT2APOLBMGMTNPSR1 | |
| SCHEMBL14086975 | 0.73 | ALDH1A1 (0.56) | MAPTBLMKMT2APOLBRAD52 | |
| SCHEMBL28855763 | 0.73 | KAT2B (0.58) | MAPTBLMKMT2APOLBL3MBTL1 | |
| SCHEMBL4236100 | 0.72 | ALDH1A1 (0.51) | MAPTKMT2APOLBATMNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291915-A1 | Silicon Compounds and Their Use | TAKEDA CAMBRIDGE LIMITED (GB) | 2009-11-26 | — | — | US | disclosed |
| US-20090291915-A1 | Silicon Compounds and Their Use | TAKEDA CAMBRIDGE LIMITED (GB) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291915-A1 | Silicon Compounds and Their Use | SOST, SIK2, SIK3 | MAPT 1051/4885BLM 268/4885KMT2A 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.