Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610548 | 0.92 | KCNH3 (0.43) | KCNH3TDP1L3MBTL1TLR8TLR7 | |
| SCHEMBL13622014 | 0.82 | MAPT (0.48) | KCNH3TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL4610708 | 0.74 | MAPT (0.43) | KCNH3L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL11698011 | 0.72 | APP (0.56) | MAPTHTTAPP | |
| SCHEMBL13752391 | 0.72 | TLR8 (0.42) | KCNH3TLR8TLR7KMT2AGBA1 | |
| SCHEMBL11675736 | 0.71 | ALDH1A1 (0.57) | KCNH3TDP1L3MBTL1MAPTHTT | |
| SCHEMBL13743236 | 0.70 | L3MBTL1 (0.37) | TDP1L3MBTL1TLR8TLR7MAPT | |
| SCHEMBL10757363 | 0.69 | TSHR (0.52) | TDP1L3MBTL1HTTHRH4HRH3 | |
| SCHEMBL11129540 | 0.69 | TSHR (0.52) | TDP1L3MBTL1MAPTHTR1AADRA1A | |
| SCHEMBL14621844 | 0.69 | P2RX3 (0.37) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291915-A1 | Silicon Compounds and Their Use | TAKEDA CAMBRIDGE LIMITED (GB) | 2009-11-26 | — | — | US | disclosed |
| US-20090291915-A1 | Silicon Compounds and Their Use | TAKEDA CAMBRIDGE LIMITED (GB) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291915-A1 | Silicon Compounds and Their Use | SOST, SIK2, SIK3 | KCNH3 1315/4885TDP1 2971/4885L3MBTL1 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.