Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | SCN1A | P35498 | 2/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24567775 | 0.80 | ANPEP (0.60) | ANPEPPKMPOLBMAPTLMNA | |
| SCHEMBL30051979 | 0.79 | MAPT (0.67) | ANPEPPKMPOLBMAPK1MAPT | |
| SCHEMBL13480572 | 0.77 | POLB (0.54) | ANPEPPKMPOLBMAPK1MAPT | |
| SCHEMBL1934232 | 0.76 | ANPEP (0.46) | ANPEPPOLBMAPK1MAPTLMNA | |
| SCHEMBL11058776 | 0.75 | POLB (0.50) | ANPEPPKMPOLBMAPK1MAPT | |
| SCHEMBL28739212 | 0.75 | TSHR (0.53) | MAPK1MAPTLMNAKMT2ASCN3A | |
| SCHEMBL6375568 | 0.75 | PKM (0.66) | PKMPOLBMAPK1LMNAKMT2A | |
| SCHEMBL14275079 | 0.74 | ATM (0.54) | ANPEPMAPK1MAPTLMNAKMT2A | |
| SCHEMBL23453327 | 0.74 | PKM (0.69) | PKMPOLBMAPK1MAPTKMT2A | |
| SCHEMBL21056124 | 0.74 | POLB (0.59) | ANPEPPKMPOLBMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286876-A1 | NEUROPROTECTIVE BENZOATE AND BENZAMIDE COMPOUNDS | SAMARITAN PHARMACEUTICALS, INC. | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286876-A1 | NEUROPROTECTIVE BENZOATE AND BENZAMIDE COMPOUNDS | ABAT, GABRB2, GABRB1 | ANPEP 166/4885PKM 1727/4885POLB 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.