Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22746450 | 0.83 | ANPEP (0.50) | ANPEPATMHSP90AA1LMNAMAPT | |
| SCHEMBL28957057 | 0.80 | SCN3A (0.50) | ANPEPATMHSP90AA1LMNAMAPT | |
| SCHEMBL28739212 | 0.78 | TSHR (0.53) | ATMHSP90AA1LMNAMAPTSCN3A | |
| SCHEMBL14275079 | 0.77 | ATM (0.54) | ANPEPATMHSP90AA1LMNAMAPT | |
| SCHEMBL22746435 | 0.76 | ANPEP (0.41) | ANPEPATMHSP90AA1LMNAMAPT | |
| SCHEMBL11673045 | 0.76 | ATM (0.49) | ANPEPATMHSP90AA1LMNAMAPT | |
| SCHEMBL7853958 | 0.76 | ATM (0.49) | ANPEPATMHSP90AA1LMNAMAPT | |
| SCHEMBL10993026 | 0.76 | ATM (0.56) | ANPEPATMHSP90AA1LMNAMAPT | |
| SCHEMBL7221331 | 0.76 | KMT2A (0.50) | ANPEPATMHSP90AA1LMNAMAPT | |
| SCHEMBL13624110 | 0.76 | ANPEP (0.56) | ANPEPLMNAMAPTSCN3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504004-B1 | PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC APPLICATIONS OF A HYDROCORTISONE DERIVATIVE DESIGNATED AS DEINA | BARCO GIOVANNI (IT) | 2015-04-15 | — | — | EP | disclosed |
| EP-2504004-A1 | PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC APPLICATIONS OF A HYDROCORTISONE DERIVATIVE DESIGNATED AS DEINA | Barco, Giovanni (IT) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011064753-A1 | PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC APPLICATIONS OF A HYDROCORTISONE DERIVATIVE DESIGNATED AS DEINA | BARCO GIOVANNI (IT) | 2011-06-03 | — | — | WO | disclosed |
| US-7816374-B2 | Administering to respiratory system an effective amount of a topical anesthetic, such as lidocaine, or a pharmaceutically acceptable salt thereof; chronic obstructive pulmonary disease | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2010-10-19 | — | — | US | disclosed |
| US-20090286876-A1 | NEUROPROTECTIVE BENZOATE AND BENZAMIDE COMPOUNDS | SAMARITAN PHARMACEUTICALS, INC. | 2009-11-19 | — | — | US | disclosed |
| US-20090054485-A1 | Method of treating neutrophil-related diseases with topical anesthetics | GLEICH GERALD J | 2009-02-26 | — | — | US | disclosed |
| US-20060167108-A1 | Neuroprotective benzoate and benzamide compounds | GEORGETOWN UNIVERSITY | 2006-07-27 | — | — | US | disclosed |
| US-20060100276-A1 | Method of treating neutrophil-related diseases with topical anesthetics | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2006-05-11 | — | — | US | disclosed |
| EP-1628649-A2 | NEUROPROTECTIVE BENZOATE AND BENZAMIDE COMPOUNDS | Samaritan Pharmaceuticals (US) | 2006-03-01 | — | — | EP | disclosed |
| US-6861449-B2 | Method of treating neutrophil-related diseases with topical anesthetics | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2005-03-01 | — | — | US | disclosed |
| EP-0682514-B1 | USE OF TOPICAL ANESTHETICS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF BRONCHIAL ASTHMA | MAYO FOUNDATION FOR MEDICAL (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2001028550-A1 | TOPICAL ANESTHETICS USEFUL FOR TREATING CANCER, AUTOIMMUNE DISEASES AND ISCHEMIA | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2001-04-26 | — | — | WO | disclosed |
| US-6071910-A | Use of agents to treat eosinophil-associated pathologies | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2000-06-06 | — | — | US | disclosed |
| EP-0979085-A1 | TREATMENT OF EOSINOPHIL-ASSOCIATED PATHOLOGIES, SUCH AS BRONCHIAL ASTHMA, WITH SYNERGISTIC COMBINATIONS OF GLUCOCORTICOIDS AND A LOCAL ANESTHETICS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2000-02-16 | — | — | EP | disclosed |
| US-5849334-A | Composition comprising a local anesthetic and emu oil and methods of use thereof | RIVLIN DANIEL (US) | 1998-12-15 | — | — | US | disclosed |
| US-5837713-A | Treatment of eosinophil-associated pathologies by administration of topical anesthetics and glucocorticoids | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1998-11-17 | — | — | US | disclosed |
| WO-1998037896-A1 | TREATMENT OF EOSINOPHIL-ASSOCIATED PATHOLOGIES, SUCH AS BRONCHIAL ASTHMA, WITH SYNERGISTIC COMBINATIONS OF GLUCOCORTICOIDS AND A LOCAL ANESTHETICS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1998-09-03 | — | — | WO | disclosed |
| US-5631267-A | BRONCHIAL ASTHMA, NASAL AND SINUS INFLAMMATION, RHINITIS, CONJUNCTIVITIS | MAYO FOUNDATION FOR MEDICAL EDUCATION & RESEARCH (US) | 1997-05-20 | — | — | US | disclosed |
| US-5510339-A | REDUCING STEROID THERAPY DEPENDENCE BY COUNTERACT THE SYMPTOMS OF ASTHMA | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1996-04-23 | — | — | US | disclosed |
| WO-1994017790-A9 | USE OF TOPICAL ANESTHETICS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF BRONCHIAL ASTHMA | — | 1994-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100276-A1 | Method of treating neutrophil-related diseases with topical anesthetics | MMP8, ELANE, MPO | ANPEP 990/4885ATM 4533/4885HSP90AA1 1456/4885 |
| US-20090286876-A1 | NEUROPROTECTIVE BENZOATE AND BENZAMIDE COMPOUNDS | ABAT, GABRB2, GABRB1 | ANPEP 166/4885ATM 1972/4885HSP90AA1 578/4885 |
| US-20060167108-A1 | Neuroprotective benzoate and benzamide compounds | ABAT, GABRB2, GABRB1 | ANPEP 166/4885ATM 1972/4885HSP90AA1 578/4885 |
| US-20090054485-A1 | Method of treating neutrophil-related diseases with topical anesthetics | MMP8, ELANE, MPO | ANPEP 990/4885ATM 4533/4885HSP90AA1 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.