Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624405 | 0.78 | POLB (0.40) | BRD4 | |
| SCHEMBL21484158 | 0.76 | PRKCB (0.34) | ALOX15CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21106863 | 0.76 | PIK3CD (0.39) | PIK3CDALOX15CHRM2CHRM4CHRM5 | |
| SCHEMBL1272035 | 0.75 | HSD17B10 (0.33) | ALOX15 | |
| SCHEMBL13624406 | 0.74 | GAA (0.38) | BRD4 | |
| SCHEMBL1272034 | 0.73 | USP19 (0.32) | — | |
| SCHEMBL13624403 | 0.73 | POLB (0.40) | ALOX15BRD4 | |
| SCHEMBL15228275 | 0.72 | CHRM2 (0.45) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13624402 | 0.72 | F10 (0.35) | — | |
| SCHEMBL14275836 | 0.71 | CHRM2 (0.33) | PIK3CDCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |