Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624405 | 0.81 | POLB (0.40) | POLBBRD4ALDH1A1MAPT | |
| SCHEMBL13652365 | 0.78 | MEN1 (0.37) | POLBBRD4KMT2AALDH1A1FKBP1A | |
| SCHEMBL13624406 | 0.78 | GAA (0.38) | BRD4KMT2AALDH1A1 | |
| SCHEMBL21945155 | 0.76 | USP19 (0.36) | BRD4 | |
| SCHEMBL13624400 | 0.73 | PIK3CD (0.32) | BRD4ALOX15 | |
| SCHEMBL27313851 | 0.73 | KMT2A (0.40) | POLBBRD4KMT2AALDH1A1MAPT | |
| SCHEMBL10767654 | 0.73 | BRD4 (0.49) | POLBBRD4KMT2AALDH1A1FKBP1A | |
| SCHEMBL2607204 | 0.73 | NCF1 (0.41) | POLBKMT2AALDH1A1MAPTPARP14 | |
| SCHEMBL18595476 | 0.73 | POLB (0.40) | POLBKMT2AALDH1A1MAPTPARP14 | |
| SCHEMBL1717843 | 0.72 | POLB (0.38) | POLBKMT2AALDH1A1FKBP1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |