Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | USP19 | O94966 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624405 | 0.83 | POLB (0.40) | GAAL3MBTL1BRD4ALDH1A1 | |
| SCHEMBL13624403 | 0.78 | POLB (0.40) | BRD4KMT2AALDH1A1 | |
| SCHEMBL13624400 | 0.74 | PIK3CD (0.32) | BRD4 | |
| SCHEMBL21484158 | 0.71 | PRKCB (0.34) | L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL21106863 | 0.71 | PIK3CD (0.39) | BRD4USP19KMT2AALDH1A1 | |
| SCHEMBL1272035 | 0.70 | HSD17B10 (0.33) | USP19 | |
| SCHEMBL13255642 | 0.70 | KEAP1 (0.43) | EPHX1MAP4K4KMT2A | |
| SCHEMBL24411659 | 0.69 | ALDH1A1 (0.35) | EPHX1MAP4K4KMT2AALDH1A1 | |
| SCHEMBL14636509 | 0.69 | POLB (0.50) | GAAL3MBTL1ALDH1A1 | |
| SCHEMBL23277738 | 0.69 | MAP4K4 (0.39) | EPHX1MAP4K4KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |