Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3491063 | 0.84 | L3MBTL1 (0.43) | POLBALDH1A1MAPTTDP1FFAR4 | |
| SCHEMBL17294311 | 0.83 | BRD4 (0.42) | POLBALDH1A1MAPTTDP1ITGB3 | |
| SCHEMBL13624406 | 0.83 | GAA (0.38) | ALDH1A1BRD4GAAL3MBTL1 | |
| SCHEMBL13624403 | 0.81 | POLB (0.40) | POLBALDH1A1MAPTBRD4 | |
| SCHEMBL13624400 | 0.78 | PIK3CD (0.32) | BRD4 | |
| SCHEMBL14636509 | 0.76 | POLB (0.50) | POLBALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL21106863 | 0.75 | PIK3CD (0.39) | POLBALDH1A1MAPTBRD4 | |
| SCHEMBL21484158 | 0.75 | PRKCB (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL1272035 | 0.73 | HSD17B10 (0.33) | — | |
| SCHEMBL21945155 | 0.72 | USP19 (0.36) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |